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Hepatic Expression of the Serine Palmitoyltransferase Subunit Sptlc2 Reduces Lipid Droplets in the Liver by Activating VLDL Secretion

OBJECTIVE: Ceramide is a signaling molecule that contributes to insulin resistance and hepatosteatosis. In the present study, we activated de novo ceramide synthesis by inducing the hepatic expression of Sptlc2 to investigate the role of ceramide in glucose and lipid metabolism. METHODS: We first co...

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Detalles Bibliográficos
Autores principales:	Kim, Goon-Tae, Kim, Su-Jung, Park, Si-Hyun, Lee, Dongyup, Park, Tae-Sik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society of Lipidology and Atherosclerosis 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379091/ https://www.ncbi.nlm.nih.gov/pubmed/32821738 http://dx.doi.org/10.12997/jla.2020.9.2.291

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