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Washing or filtering of blood products does not improve outcome in a rat model of trauma and multiple transfusion

BACKGROUND: Transfusion is associated with organ failure and nosocomial infection in trauma patients, which may be mediated by soluble bioactive substances in blood products, including extracellular vesicles (EVs). We hypothesize that removing EVs, by washing or filtering of blood products, reduces...

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Detalles Bibliográficos
Autores principales:	Wirtz, Mathijs R., Jurgens, Jordy, Zuurbier, Coert J., Roelofs, Joris J.T.H., Spinella, Philip C., Muszynski, Jennifer A., Carel Goslings, J., Juffermans, Nicole P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2018
Materias:	Transfusion Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379301/ https://www.ncbi.nlm.nih.gov/pubmed/30461025 http://dx.doi.org/10.1111/trf.15039

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