Cargando…

Hyperoside Protected Against Oxidative Stress-Induced Liver Injury via the PHLPP2-AKT-GSK-3β Signaling Pathway In Vivo and In Vitro

Hyperoside, isolated from Drosera rotundifolia L., seeds of Cuscuta chinensis Lam., or Hypericum perforatum L., originally showed to possess an antifungal and antibacterial activity, while recently showed the protective effects against oxidative stress-induced liver injury. This study investigated s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xing, Haiyan, Fu, Ruoqiu, Cheng, Caiyi, Cai, Yongqing, Wang, Xianfeng, Deng, Dongmei, Gong, Xiaoyuan, Chen, Jianhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379337/ https://www.ncbi.nlm.nih.gov/pubmed/32765271 http://dx.doi.org/10.3389/fphar.2020.01065

Ejemplares similares

Crm1-Dependent Nuclear Export of Bach1 is Involved in the Protective Effect of Hyperoside on Oxidative Damage in Hepatocytes and CCl(4)-induced Acute Liver Injury
por: Cai, Yongqing, et al.
Publicado: (2021)

Successful Treatment With Intrathecal and Intravenous Polymyxin B-Based Combination Against MDR Acinetobacter baumannii Meningitis in Pediatric Patient: A Case Report
por: Xing, Haiyan, et al.
Publicado: (2021)

Hyperoside Ameliorates Diabetic Retinopathy via Anti-Oxidation, Inhibiting Cell Damage and Apoptosis Induced by High Glucose
por: Wu, Wei, et al.
Publicado: (2020)

Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice
por: Huang, Jizhen, et al.
Publicado: (2020)

Hyperoside Protects Human Umbilical Vein Endothelial Cells Against Anticardiolipin Antibody-Induced Injury by Activating Autophagy
por: Wei, Aiwu, et al.
Publicado: (2020)

The Cytoprotective Effect of Hyperoside against Oxidative Stress Is Mediated by the Nrf2-ARE Signaling Pathway through GSK-3β Inactivation
por: Xing, Hai-Yan, et al.
Publicado: (2015)

Biejiajian Pill Inhibits Carcinogenesis and Metastasis via the Akt/GSK-3β/Snail Signaling Pathway in Hepatocellular Carcinoma
por: Sun, Jialing, et al.
Publicado: (2021)

Potential Implications of Hyperoside on Oxidative Stress-Induced Human Diseases: A Comprehensive Review
por: Wang, Kaiyang, et al.
Publicado: (2023)

Modified Sijunzi Decoction Inhibits Epithelial-Mesenchymal Transition of Non-Small Cell Lung Cancer by Attenuating AKT/GSK3β Pathway in vitro and in vivo
por: Shao, Niu, et al.
Publicado: (2022)

Isoorientin Ameliorates APAP-Induced Hepatotoxicity via Activation Nrf2 Antioxidative Pathway: The Involvement of AMPK/Akt/GSK3β
por: Fan, Xiaoye, et al.
Publicado: (2018)

Recent Developments in Pharmacological Effect, Mechanism and Application Prospect of Diazeniumdiolates
por: Li, Bin, et al.
Publicado: (2020)

SCD1 Confers Temozolomide Resistance to Human Glioma Cells via the Akt/GSK3β/β-Catenin Signaling Axis
por: Dai, Shuang, et al.
Publicado: (2018)

Mutual inhibition of insulin signaling and PHLPP-1 determines cardioprotective efficiency of Akt in aged heart
por: Xing, Yuan, et al.
Publicado: (2016)

Corrigendum: SCD1 Confers Temozolomide Resistance to Human Glioma Cells Via the Akt/GSK3β/β-Catenin Signaling Axis
por: Dai, Shuang, et al.
Publicado: (2019)

Metabolic Engineering of Escherichia coli for Hyperoside Biosynthesis
por: Li, Guosi, et al.
Publicado: (2022)

Fisetin Inhibited Growth and Metastasis of Triple-Negative Breast Cancer by Reversing Epithelial-to-Mesenchymal Transition via PTEN/Akt/GSK3β Signal Pathway
por: Li, Jie, et al.
Publicado: (2018)

FKBP51 plays an essential role in Akt ubiquitination that requires Hsp90 and PHLPP
por: Tufano, Martina, et al.
Publicado: (2023)

Estradiol Activates PI3K/Akt/GSK3 Pathway Under Chronic Neurodegenerative Conditions Triggered by Perinatal Asphyxia
por: Saraceno, G. Ezequiel, et al.
Publicado: (2018)

Astragaloside IV Alleviates Intestinal Barrier Dysfunction via the AKT-GSK3β-β-Catenin Pathway in Peritoneal Dialysis
por: He, Jiaqi, et al.
Publicado: (2022)

Water extract of cacumen platycladi promotes hair growth through the Akt/GSK3β/β-catenin signaling pathway
por: Fu, Hangjie, et al.
Publicado: (2023)

Emerging roles of PHLPP phosphatases in lung cancer
por: Xia, Xinhang, et al.
Publicado: (2023)

Protective effects of quercetin and hyperoside on renal fibrosis in rats with unilateral ureteral obstruction
por: YAN, YANG, et al.
Publicado: (2014)

Resveratrol Attenuates High Glucose-Induced Osteoblast Dysfunction via AKT/GSK3β/FYN-Mediated NRF2 Activation
por: Xuan, Yue, et al.
Publicado: (2022)

Corrigendum: Water extract of cacumen platycladi promotes hair growth through the Akt/GSK3β/β-catenin signaling pathway
por: Fu, Hangjie, et al.
Publicado: (2023)

Detection of PHLPP1α/β in Human and Mouse Brain by Different Anti-PHLPP1 Antibodies
por: Jackson, Travis C., et al.
Publicado: (2015)

Xuebijing Protects Against Septic Acute Liver Injury Based on Regulation of GSK-3β Pathway
por: Cao, Liping, et al.
Publicado: (2021)

USP46 Inhibits Cell Proliferation in Lung Cancer through PHLPP1/AKT Pathway
por: Wang, Wei, et al.
Publicado: (2020)

PHLPP1 Overexpression was Associated With a Good Prognosis With Decreased AKT Activity in Gastric Cancer
por: Park, Sun Yi, et al.
Publicado: (2022)

Integrating network pharmacology prediction and experimental investigation to verify ginkgetin anti-invasion and metastasis of human lung adenocarcinoma cells via the Akt/GSK-3β/Snail and Wnt/β-catenin pathway
por: Liu, Kaile, et al.
Publicado: (2023)

Emerging roles of PHLPP phosphatases in metabolism
por: Cha, Jong-Ho, et al.
Publicado: (2021)

Chondrocytic and pharmacokinetic properties of Phlpp inhibitors
por: Taylor, E.L., et al.
Publicado: (2021)

Preparation and Properties of Cyclodextrin Inclusion Complexes of Hyperoside
por: Zhang, Xinyu, et al.
Publicado: (2022)

Aberrant Expression of PHLPP1 and PHLPP2 Correlates with Poor Prognosis in Patients with Hypopharyngeal Squamous Cell Carcinoma
por: Zhou, Jieyu, et al.
Publicado: (2015)

Dec1 Deficiency Ameliorates Pulmonary Fibrosis Through the PI3K/AKT/GSK-3β/β-Catenin Integrated Signaling Pathway
por: Hu, Xingxing, et al.
Publicado: (2022)

PHLPP1 deficiency protects against age‐related intervertebral disc degeneration
por: Zhang, Changli, et al.
Publicado: (2022)

Hyperoside protects the blood-brain barrier from neurotoxicity of amyloid beta 1–42
por: Liu, Chen-Yang, et al.
Publicado: (2018)

Momordica charantia Exosome-Like Nanoparticles Exert Neuroprotective Effects Against Ischemic Brain Injury via Inhibiting Matrix Metalloproteinase 9 and Activating the AKT/GSK3β Signaling Pathway
por: Cai, Heng, et al.
Publicado: (2022)

Increased therapeutic efficacy of combination of azithromycin and ceftazidime on Pseudomonas aeruginosa biofilm in an animal model of ureteral stent infection
por: Wang, Xianfeng, et al.
Publicado: (2016)

Sodium Dichloroacetate Stimulates Angiogenesis by Improving Endothelial Precursor Cell Function in an AKT/GSK-3β/Nrf2 Dependent Pathway in Vascular Dementia Rats
por: Zhao, Hui, et al.
Publicado: (2019)

Paeoniflorin Inhibits Mesangial Cell Proliferation and Inflammatory Response in Rats With Mesangial Proliferative Glomerulonephritis Through PI3K/AKT/GSK-3β Pathway
por: Liu, Bihao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vnk19li49ebr981lbjrsnb6sru