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Early‐onset inflammatory bowel disease as a model disease to identify key regulators of immune homeostasis mechanisms

Rare, monogenetic diseases present unique models to dissect gene functions and biological pathways, concomitantly enhancing our understanding of the etiology of complex (and often more common) traits. Although inflammatory bowel disease (IBD) is a generally prototypic complex disease, it can also ma...

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Detalles Bibliográficos
Autores principales: Pazmandi, Julia, Kalinichenko, Artem, Ardy, Rico Chandra, Boztug, Kaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379380/
https://www.ncbi.nlm.nih.gov/pubmed/30565237
http://dx.doi.org/10.1111/imr.12726