Treatment with lecinoxoids attenuates focal and segmental glomerulosclerosis development in nephrectomized rats

Focal segmental glomerulosclerosis (FSGS) is a scarring process associated with chronic low‐grade inflammation ascribed to toll‐like receptor (TLR) activation and monocyte migration. We developed synthetic, small‐molecule lecinoxoids, VB‐201 and VB‐703, that differentially inhibit TLR‐2‐ and TLR‐4‐m...

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Detalles Bibliográficos
Autores principales: Yacov, Niva, Feldman, Boris, Volkov, Alexander, Ishai, Eti, Breitbart, Eyal, Mendel, Itzhak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379519/
https://www.ncbi.nlm.nih.gov/pubmed/30125459
http://dx.doi.org/10.1111/bcpt.13114

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