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Factor XII truncation accelerates activation in solution

ESSENTIALS: During contact system activation, factor XII is progressively cleaved by plasma kallikrein. We investigated the role of factor XII truncation in biochemical studies. Factor XII contains naturally occurring truncating cleavage sites for a variety of enzymes. Truncation of factor XII prime...

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Detalles Bibliográficos
Autores principales:	de Maat, S., Clark, C. C., Boertien, M., Parr, N., Sanrattana, W., Hofman, Z. L. M., Maas, C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	COAGULATION
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379707/ https://www.ncbi.nlm.nih.gov/pubmed/30394658 http://dx.doi.org/10.1111/jth.14325

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