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MicroRNA-410-3p modulates chondrocyte apoptosis and inflammation by targeting high mobility group box 1 (HMGB1) in an osteoarthritis mouse model

BACKGROUND: Osteoarthritis (OA) is the most prevalent type of arthritis, which commonly involves inflammation in the articular cartilage in OA pathogenesis. MicroRNAs (miRNAs) play essential roles in the regulation and pathophysiology of various diseases including OA. MiR-410-3p has been demonstrate...

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Detalles Bibliográficos
Autores principales: Pan, Hong, Dai, Huming, Wang, Linzhi, Lin, Silong, Tao, Yuefeng, Zheng, Yi, Jiang, Renyi, Fang, Fan, Wu, Yifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379779/
https://www.ncbi.nlm.nih.gov/pubmed/32709223
http://dx.doi.org/10.1186/s12891-020-03489-7