Cargando…

Ninjin'yoeito Targets Distinct Ca(2+) Channels to Activate Ghrelin-Responsive vs. Unresponsive NPY Neurons in the Arcuate Nucleus

Appetite loss or anorexia substantially deteriorates quality of life in various diseases, and stand upstream of frailty. Neuropeptide Y (NPY) in the hypothalamic arcuate nucleus (ARC) and ghrelin released from stomach are potent inducers of appetite. We previously reported that Ninjin'yoeito, a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Goswami, Chayon, Dezaki, Katsuya, Wang, Lei, Inui, Akio, Seino, Yutaka, Yada, Toshihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Nutrition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379896/ https://www.ncbi.nlm.nih.gov/pubmed/32766273 http://dx.doi.org/10.3389/fnut.2020.00104

Ejemplares similares

Improvement of Diabetes Mellitus Symptoms by Intake of Ninjin'yoeito
por: Hosogi, Shigekuni, et al.
Publicado: (2018)

Herbal Medicine Ninjin'yoeito in the Treatment of Sarcopenia and Frailty
por: Uto, Nanami Sameshima, et al.
Publicado: (2018)

A Clinical Study of Ninjin'yoeito With Regard to Frailty
por: Sakisaka, Naoya, et al.
Publicado: (2018)

Analysis of the Effects of Ninjin’yoeito on Physical Frailty in Mice
por: Otsuka, Shotaro, et al.
Publicado: (2022)

Ninjin’yoeito Improves Genitourinary Symptoms in Patients With Frailty
por: Okui, Nobuo, et al.
Publicado: (2023)

Impact of Ninjin’yoeito on frailty and short life in klotho-hypomorphic (kl/kl) mice
por: Amitani, Haruka, et al.
Publicado: (2022)

Safety and Effectiveness of Ninjin'yoeito: A Utilization Study in Elderly Patients
por: Suzuki, Shinichi, et al.
Publicado: (2019)

Case Report: Efficacy of Ninjin'yoeito Treatment for Idiopathic Pulmonary Fibrosis
por: Kushima, Hisako, et al.
Publicado: (2021)

Effect of Ninjin’yoeito on the Loss of Skeletal Muscle Function in Cancer-Bearing Mice
por: Ohsawa, Masahiro, et al.
Publicado: (2018)

Ninjin'yoeito Alleviates Neuropathic Pain Induced by Chronic Constriction Injury in Rats
por: Takemoto, Risa, et al.
Publicado: (2021)

Perspectives on the Use of Ninjin'yoeito in Modern Medicine: A Review of Randomized Controlled Trials
por: Takayama, Shin, et al.
Publicado: (2019)

Maintaining Weight and Nutritional Status with Ninjin’yoeito in Elderly Patients with Chronic Wasting Diseases
por: Nakagawa, Yumi, et al.
Publicado: (2022)

Efficacy of Ninjin'yoeito in treating severe coronavirus disease 2019 in patients in an intensive care unit
por: Aomatsu, Naoki, et al.
Publicado: (2021)

Ninjin’yoeito suppressed the onset of arthritis, pain, and muscle atrophy in rheumatoid arthritis model mice
por: Suginohara, Takeshi, et al.
Publicado: (2022)

Effects of Ninjin'yoeito on Human CYP3A and Mouse CYP3A Activity
por: Kaneda, Marisa, et al.
Publicado: (2023)

Japanese Kampo medicine ninjin'yoeito synergistically enhances tumor vaccine effects mediated by CD8(+) T cells
por: Takaku, Shun, et al.
Publicado: (2017)

Case Report: Ninjin'yoeito May Improve Quality of Life After Hospitalization for Acute Illness in Patients With Frailty
por: Kashima, Masayuki
Publicado: (2021)

Combined Use of Ninjin'yoeito Improves Subjective Fatigue Caused by Lenalidomide in Patients With Multiple Myeloma: A Retrospective Study
por: Ito, Tomoki, et al.
Publicado: (2018)

Influence of Intragastric Administration of Traditional Japanese Medicine, Ninjin'Yoeito, on Cerebral Blood Flow via Muscarinic Acetylcholine Receptors
por: Watanabe, Nobuhiro, et al.
Publicado: (2021)

The effects of ninjin’yoeito on the electrophysiological properties of dopamine neurons in the ventral tegmental area/substantia nigra pars compacta and medium spiny neurons in the nucleus accumbens
por: Imai, Ryota, et al.
Publicado: (2022)

Improvement in Frailty in a Patient With Severe Chronic Obstructive Pulmonary Disease After Ninjin'yoeito Therapy: A Case Report
por: Kuniaki, Hirai, et al.
Publicado: (2018)

Evaluation of Effect of Ninjin'yoeito on Regional Brain Glucose Metabolism by (18)F-FDG Autoradiography With Insulin Loading in Aged Mice
por: Zhao, Jingmin, et al.
Publicado: (2021)

Postoperative Adjuvant Chemotherapy Regimen of CAPOX Combined With Ninjin'yoeito in an Elderly Patient With Stage III Colon Cancer: A Case Report
por: Aomatsu, Naoki, et al.
Publicado: (2020)

Case Report: Prolonged Anorexia With Nausea Caused by Immune Checkpoint Inhibitors for Malignant Melanoma Treated Using Kampo Medicines Bukuryoingohangekobokuto and Ninjin’yoeito
por: Takayama, Shin, et al.
Publicado: (2022)

Ninjin’yoeito ameliorated PPE-induced pulmonary emphysema and anxiety/depressive-like behavior in aged C57BL/6J mice
por: Shimoyama, Taiki, et al.
Publicado: (2022)

Frailty Improvement by Multicomponent Drug, Ninjin’Yoeito, in Mild Cognitive Impairment and Mild Alzheimer’s Disease Patients: An Open-Label Exploratory Study (FRAMINGO)
por: Okahara, Kazunori, et al.
Publicado: (2023)

Ninjin’yoeito Ameliorates Skeletal Muscle Complications in COPD Model Mice by Upregulating Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Expression
por: Miyamoto, Atsushi, et al.
Publicado: (2020)

A Possibility of Simultaneous Treatment with the Multicomponent Drug, Ninjin’yoeito, for Anorexia, Apathy, and Cognitive Dysfunction in Frail Alzheimer’s Disease Patients: An Open-Label Pilot Study
por: Ohsawa, Makoto, et al.
Publicado: (2017)

Immunological Differences in Human Peripheral Blood Mononuclear Cells Treated with Traditional Japanese Herbal Medicines Hochuekkito, Juzentaihoto, and Ninjin'yoeito from Different Pharmaceutical Companies
por: Kiyomi, Anna, et al.
Publicado: (2021)

Oral Administration of Ren-Shen-Yang-Rong-Tang ‘Ninjin’yoeito’ Protects Against Hematotoxicity and Induces Immature Erythroid Progenitor Cells in 5-Fluorouracil-induced Anemia
por: Takano, Fumihide, et al.
Publicado: (2009)

Good Rehabilitation Outcomes and Improved Nutritional Status After Treatment With the Japanese Herbal Medicine Ninjin'yoeito in an Elderly Patient With Hip Fracture and Sarcopenia: A Case Report
por: Morinaga, Akinori, et al.
Publicado: (2020)

Ninjin’yoeito, a traditional Japanese Kampo medicine, suppresses the onset of anhedonia induced by dysfunction in the striatal dopamine receptor type 2-expressing medium spiny neurons
por: Oizumi, Hiroaki, et al.
Publicado: (2021)

Liver Injury by the Traditional Chinese Medicine Hanshirento, Zenshikunshito, and Ninjin’yoeito in a Patient with Lung Cancer: Probable Causality Assessed by the Updated Roussel Uclaf Causality Assessment Method
por: Funakoshi, Haruki, et al.
Publicado: (2021)

Insulin suppresses ghrelin-induced calcium signaling in neuropeptide Y neurons of the hypothalamic arcuate nucleus
por: Maejima, Yuko, et al.
Publicado: (2011)

Impact of Ninjin'Yoeito on Fatigue in Patients Receiving Nab-Paclitaxel Plus Gemcitabine Therapy: A Prospective, Single-Arm, Phase II Open Label, Nonrandomized, Historically-Controlled Study
por: Okada, Ken-ichi, et al.
Publicado: (2020)

Safety and efficacy of Ninjin’yoeito along with iron supplementation therapy for preoperative anemia, fatigue, and anxiety in patients with gynecological disease: an open-label, single-center, randomized phase-II trial
por: Yagi, Taro, et al.
Publicado: (2022)

d-Allulose Inhibits Ghrelin-Responsive, Glucose-Sensitive and Neuropeptide Y Neurons in the Arcuate Nucleus and Central Injection Suppresses Appetite-Associated Food Intake in Mice
por: Rakhat, Yermek, et al.
Publicado: (2022)

Comparative study of the effects of the three kinds of Kampo-hozai: Ninjinyoeito, Hochuekkito, and Juzentaihoto on anxious and low sociability behavior using NPY-knockout zebrafish
por: Kawabe, Momoko, et al.
Publicado: (2023)

Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin
por: Paeger, Lars, et al.
Publicado: (2017)

NPY and VGF Immunoreactivity Increased in the Arcuate Nucleus, but Decreased in the Nucleus of the Tractus Solitarius, of Type-II Diabetic Patients
por: Saderi, Nadia, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_o7irpi97h3eqho67jqnua3p7q8