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A nonmyeloablative chimeric mouse model accurately defines microglia and macrophage contribution in glioma
AIMS: Resident and peripherally derived glioma associated microglia/macrophages (GAMM) play a key role in driving tumour progression, angiogenesis, invasion and attenuating host immune responses. Differentiating these cells’ origins is challenging and current preclinical models such as irradiation‐b...
Autores principales: | Yu, K., Youshani, A. S., Wilkinson, F. L., O'Leary, C., Cook, P., Laaniste, L., Liao, A., Mosses, D., Waugh, C., Shorrock, H., Pathmanaban, O., Macdonald, A., Kamaly‐Asl, I., Roncaroli, F., Bigger, B. W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379954/ https://www.ncbi.nlm.nih.gov/pubmed/29679380 http://dx.doi.org/10.1111/nan.12489 |
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