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A nonmyeloablative chimeric mouse model accurately defines microglia and macrophage contribution in glioma

AIMS: Resident and peripherally derived glioma associated microglia/macrophages (GAMM) play a key role in driving tumour progression, angiogenesis, invasion and attenuating host immune responses. Differentiating these cells’ origins is challenging and current preclinical models such as irradiation‐b...

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Detalles Bibliográficos
Autores principales: Yu, K., Youshani, A. S., Wilkinson, F. L., O'Leary, C., Cook, P., Laaniste, L., Liao, A., Mosses, D., Waugh, C., Shorrock, H., Pathmanaban, O., Macdonald, A., Kamaly‐Asl, I., Roncaroli, F., Bigger, B. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379954/
https://www.ncbi.nlm.nih.gov/pubmed/29679380
http://dx.doi.org/10.1111/nan.12489

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