Propeptide glycosylation and galectin‐3 binding decrease proteolytic activation of human proMMP‐9/progelatinase B

Matrix metalloproteinases (MMPs) are secreted as proenzymes, containing propeptides that interact with the catalytic zinc, thereby controlling MMP activation. The MMP‐9 propeptide is unique in the MMP family because of its post‐translational modification with an N‐linked oligosaccharide. ProMMP‐9 ac...

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Detalles Bibliográficos
Autores principales: Boon, Lise, Ugarte‐Berzal, Estefania, Martens, Erik, Vandooren, Jennifer, Rybakin, Vasily, Colau, Didier, Gordon‐Alonso, Monica, van der Bruggen, Pierre, Stöcker, Walter, Becker‐Pauly, Christoph, Witters, Peter, Morava, Eva, Jaeken, Jaak, Proost, Paul, Opdenakker, Ghislain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379967/
https://www.ncbi.nlm.nih.gov/pubmed/30422384
http://dx.doi.org/10.1111/febs.14698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379967/
https://www.ncbi.nlm.nih.gov/pubmed/30422384
http://dx.doi.org/10.1111/febs.14698

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