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Performance of a recombinant fusion protein linking coagulation factor IX with recombinant albumin in one‐stage clotting assays

ESSENTIALS: Performance of the one‐stage clotting (OSC) assay varies with the clotting activator used. Recombinant FIX‐albumin fusion protein (rIX‐FP) was reliably monitored with most OSC reagents. rIX‐FP shows comparable reagent‐dependent variability to other rFIX products in the OSC assay. Actin(®...

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Detalles Bibliográficos
Autores principales: Horn, C., Négrier, C., Kalina, U., Seifert, W., Friedman, K. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379984/
https://www.ncbi.nlm.nih.gov/pubmed/30418692
http://dx.doi.org/10.1111/jth.14332