Cargando…

Performance of a recombinant fusion protein linking coagulation factor IX with recombinant albumin in one‐stage clotting assays

ESSENTIALS: Performance of the one‐stage clotting (OSC) assay varies with the clotting activator used. Recombinant FIX‐albumin fusion protein (rIX‐FP) was reliably monitored with most OSC reagents. rIX‐FP shows comparable reagent‐dependent variability to other rFIX products in the OSC assay. Actin(®...

Descripción completa

Detalles Bibliográficos
Autores principales:	Horn, C., Négrier, C., Kalina, U., Seifert, W., Friedman, K. D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	COAGULATION
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379984/ https://www.ncbi.nlm.nih.gov/pubmed/30418692 http://dx.doi.org/10.1111/jth.14332

Ejemplares similares

Long-Acting Recombinant Fusion Protein Linking Coagulation Factor IX with Albumin (rIX-FP) in Children: Results of a Phase 3 Trial
por: Kenet, Gili, et al.
Publicado: (2016)

Pharmacological characteristics of a novel, recombinant fusion protein linking coagulation factor VIIa with albumin (rVIIa-FP)
por: Zollner, S, et al.
Publicado: (2014)

Biochemical and functional characterization of a recombinant monomeric factor VIII–Fc fusion protein
por: PETERS, R T, et al.
Publicado: (2013)

Coagulation factor XII protease domain crystal structure
por: Pathak, M, et al.
Publicado: (2015)

Pharmacokinetics of Recombinant Human Soluble Thrombomodulin in Disseminated Intravascular Coagulation Patients with Acute Renal Dysfunction
por: Hayakawa, Mineji, et al.
Publicado: (2017)

Identification of aggregates in therapeutic formulations of recombinant full‐length factor VIII products by sedimentation velocity analytical ultracentrifugation
por: Healey, J. F., et al.
Publicado: (2018)

Crosslinked clots formed independently of factor XIII and without fibrinogen‐to‐fibrin conversion – is this a liver‐specific phenomenon?
por: Lisman, T.
Publicado: (2018)

Recurrent venous thromboembolism patients form clots with lower elastic modulus than those formed by patients with non‐recurrent disease
por: Baker, Stephen R., et al.
Publicado: (2019)

Sirtilins – the new old members of the vitamin K‐dependent coagulation factor family
por: Dahms, Sven O., et al.
Publicado: (2019)

Assessment of the protein interaction between coagulation factor XII and corn trypsin inhibitor by molecular docking and biochemical validation
por: Hamad, B. K., et al.
Publicado: (2017)

An engineered U1 small nuclear RNA rescues splicing-defective coagulation F7 gene expression in mice
por: Balestra, D, et al.
Publicado: (2014)

Plasma free fatty acid levels influence Zn(2+)-dependent histidine-rich glycoprotein–heparin interactions via an allosteric switch on serum albumin
por: Kassaar, O, et al.
Publicado: (2015)

Impact of Fibrinogen Carbamylation on Fibrin Clot Formation and Stability
por: Binder, Veronika, et al.
Publicado: (2017)

Factor XII truncation accelerates activation in solution
por: de Maat, S., et al.
Publicado: (2018)

A simple flow cytometry method improves the detection of phosphatidylserine-exposing extracellular vesicles
por: Arraud, N, et al.
Publicado: (2015)

Myeloid but not epithelial tissue factor exerts protective anti‐inflammatory effects in acid aspiration‐induced acute lung injury
por: Kral‐Pointner, J. B., et al.
Publicado: (2017)

Dexamethasone inhibits endotoxin‐induced coagulopathy in human lungs
por: Bartko, J., et al.
Publicado: (2016)

Novel factor VIII variants with a modified furin cleavage site improve the efficacy of gene therapy for hemophilia A
por: Nguyen, G. N., et al.
Publicado: (2016)

The role of β‐barrels 1 and 2 in the enzymatic activity of factor XIII A‐subunit
por: Hethershaw, E. L., et al.
Publicado: (2018)

Towards patient‐specific management of trauma hemorrhage: the effect of resuscitation therapy on parameters of thromboelastometry
por: Juffermans, Nicole P., et al.
Publicado: (2019)

Redox control of β(2)-glycoprotein I–von Willebrand factor interaction by thioredoxin-1
por: PASSAM, F H, et al.
Publicado: (2010)

Genomeâwide analysis of genetic determinants of circulating factorÂVIIâactivating protease (FSAP) activity
por: Olsson, M., et al.
Publicado: (2018)

A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X
por: TAI, S J, et al.
Publicado: (2008)

The thrombomodulin analog Solulin promotes reperfusion and reduces infarct volume in a thrombotic stroke model
por: SU, E J, et al.
Publicado: (2011)

Four‐factor prothrombin complex concentrate reverses apixaban‐associated bleeding in a rabbit model of acute hemorrhage
por: Herzog, E., et al.
Publicado: (2015)

Novel, high incidence exercise-induced muscle bleeding model in hemophilia B mice: rationale, development and prophylactic intervention
por: Tranholm, M, et al.
Publicado: (2015)

Conformational quiescence of ADAMTS‐13 prevents proteolytic promiscuity
por: South, K., et al.
Publicado: (2016)

Androgen receptor dampens tissue factor expression via nuclear factor‐κB and early growth response protein 1
por: Hoesel, B., et al.
Publicado: (2018)

Half-life–extended recombinant coagulation factor IX–albumin fusion protein is recycled via the FcRn-mediated pathway
por: Chia, Jenny, et al.
Publicado: (2018)

Results of a phase I/II open-label, safety and efficacy trial of coagulation factor IX (recombinant), albumin fusion protein in haemophilia B patients
por: Martinowitz, U, et al.
Publicado: (2015)

IDEAL study: A real‐world assessment of pattern of use and clinical outcomes with recombinant coagulation factor IX albumin fusion protein (rIX‐FP) in patients with haemophilia B in Italy
por: Tagliaferri, Annarita, et al.
Publicado: (2022)

Inflammation, infection and coagulation disorders
por: Sandset, Per Morten
Publicado: (2019)

Biodistribution of recombinant factor IX, extended half-life recombinant factor IX Fc fusion protein, and glycoPEGylated recombinant factor IX in hemophilia B mice
por: van der Flier, Arjan, et al.
Publicado: (2023)

Evidence of protective effects of recombinant ADAMTS13 in a humanized model of sickle cell disease
por: Rossato, Paolo, et al.
Publicado: (2022)

Coagulation Dysfunction and Hematological Changes in 633 Patients with COVID-19
por: Yang, Mo, et al.
Publicado: (2020)

Fusion of engineered albumin with factor IX Padua extends half‐life and improves coagulant activity
por: Lombardi, Silvia, et al.
Publicado: (2021)

Polyphosphate Delays Fibrin Polymerisation and Alters the Mechanical Properties of the Fibrin Network
por: Whyte, Claire S., et al.
Publicado: (2016)

Are Cardiovascular Risk Factors also Associated with the Incidence of Atrial Fibrillation?: A Systematic Review and Field Synopsis of 23 Factors in 32 Population-Based Cohorts of 20 Million Participants
por: Allan, Victoria, et al.
Publicado: (2017)

Platelet Turnover Predicts Outcome after Coronary Intervention
por: Freynhofer, Matthias K., et al.
Publicado: (2017)

Switching warfarin patients to a direct oral anticoagulant during the Coronavirus Disease-19 pandemic
por: Patel, Rachna, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cmiakteijfd9ctli2tdjq0p2ej