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Murine type VII collagen distorts outcome in human skin graft mouse model for dystrophic epidermolysis bullosa

Human skin graft mouse models are widely used to investigate and develop therapeutic strategies for the severe generalized form of recessive dystrophic epidermolysis bullosa (RDEB), which is caused by biallelic null mutations in COL7A1 and the complete absence of type VII collagen (C7). Most therape...

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Detalles Bibliográficos
Autores principales: Bremer, Jeroen, Kramer, Duco, Eichhorn, Daryll S., Gostyński, Antoni, Diercks, Gilles F. H., Jonkman, Marcel F., van den Akker, Peter C., Pasmooij, Anna M. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380020/
https://www.ncbi.nlm.nih.gov/pubmed/30019435
http://dx.doi.org/10.1111/exd.13744

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