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TLR7 Stimulation With Imiquimod Induces Selective Autophagy and Controls Mycobacterium tuberculosis Growth in Mouse Macrophages

Autophagy is a lysosomal self-digestion pathway that maintains internal homeostasis inside cells and critical process by which the innate immune system eliminates intracellular bacteria. In this study, we showed that stimulation of toll-like receptor 7 (TLR7) with imiquimod (IMQ) triggered autophagi...

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Detalles Bibliográficos
Autores principales: Lee, Hyo-Ji, Kang, Su-Jin, Woo, Yunseo, Hahn, Tae-Wook, Ko, Hyun-Jeong, Jung, Yu-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380068/
https://www.ncbi.nlm.nih.gov/pubmed/32765474
http://dx.doi.org/10.3389/fmicb.2020.01684