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Approach to critical illness myopathy and polyneuropathy in the older SARS-CoV-2 patients

One of the major concerns of the health care community and the public surrounding the SARS-CoV-2 pandemic is the availability and use of ventilators. Unprecedented surges of patients presented to intensive care units across the country, with older adults making up a large proportion of the patient p...

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Autores principales: McClafferty, Brendan, Umer, Ibrahim, Fye, Gary, Kepko, Douglas, Kalayanamitra, Ricci, Shahid, Zainab, Ramgobin, Devyani, Cai, Alice, Groff, Andrew, Bhandari, Abani, Aggarwal, Chander Shekher, Patel, Ravi, Bhatt, Dhirisha, Polimera, Hyma, Sahu, Nitasa, Vunnam, Ramarao, Golamari, Reshma, Kumar, Ashutosh, Jain, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380205/
https://www.ncbi.nlm.nih.gov/pubmed/33070904
http://dx.doi.org/10.1016/j.jocn.2020.07.058
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author McClafferty, Brendan
Umer, Ibrahim
Fye, Gary
Kepko, Douglas
Kalayanamitra, Ricci
Shahid, Zainab
Ramgobin, Devyani
Cai, Alice
Groff, Andrew
Bhandari, Abani
Aggarwal, Chander Shekher
Patel, Ravi
Bhatt, Dhirisha
Polimera, Hyma
Sahu, Nitasa
Vunnam, Ramarao
Golamari, Reshma
Kumar, Ashutosh
Jain, Rohit
author_facet McClafferty, Brendan
Umer, Ibrahim
Fye, Gary
Kepko, Douglas
Kalayanamitra, Ricci
Shahid, Zainab
Ramgobin, Devyani
Cai, Alice
Groff, Andrew
Bhandari, Abani
Aggarwal, Chander Shekher
Patel, Ravi
Bhatt, Dhirisha
Polimera, Hyma
Sahu, Nitasa
Vunnam, Ramarao
Golamari, Reshma
Kumar, Ashutosh
Jain, Rohit
author_sort McClafferty, Brendan
collection PubMed
description One of the major concerns of the health care community and the public surrounding the SARS-CoV-2 pandemic is the availability and use of ventilators. Unprecedented surges of patients presented to intensive care units across the country, with older adults making up a large proportion of the patient population. This paper illustrates contemporary approaches to critical illness myopathy (CIM), critical illness polyneuropathy (CIP), and critical illness polyneuromyopathy (CIPNM) in older patients, including incidence, risk factors, mechanisms for pathology, diagnosis, contemporary treatment approaches, and outcomes. We hope that the following analysis may help educate clinicians and ultimately decrease the duration of the mechanical ventilation required by these patients, resulting in improved clinical outcomes and an increase in ventilator availability for other patients in need.
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spelling pubmed-73802052020-07-24 Approach to critical illness myopathy and polyneuropathy in the older SARS-CoV-2 patients McClafferty, Brendan Umer, Ibrahim Fye, Gary Kepko, Douglas Kalayanamitra, Ricci Shahid, Zainab Ramgobin, Devyani Cai, Alice Groff, Andrew Bhandari, Abani Aggarwal, Chander Shekher Patel, Ravi Bhatt, Dhirisha Polimera, Hyma Sahu, Nitasa Vunnam, Ramarao Golamari, Reshma Kumar, Ashutosh Jain, Rohit J Clin Neurosci Review Article One of the major concerns of the health care community and the public surrounding the SARS-CoV-2 pandemic is the availability and use of ventilators. Unprecedented surges of patients presented to intensive care units across the country, with older adults making up a large proportion of the patient population. This paper illustrates contemporary approaches to critical illness myopathy (CIM), critical illness polyneuropathy (CIP), and critical illness polyneuromyopathy (CIPNM) in older patients, including incidence, risk factors, mechanisms for pathology, diagnosis, contemporary treatment approaches, and outcomes. We hope that the following analysis may help educate clinicians and ultimately decrease the duration of the mechanical ventilation required by these patients, resulting in improved clinical outcomes and an increase in ventilator availability for other patients in need. Elsevier Ltd. 2020-09 2020-07-24 /pmc/articles/PMC7380205/ /pubmed/33070904 http://dx.doi.org/10.1016/j.jocn.2020.07.058 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review Article
McClafferty, Brendan
Umer, Ibrahim
Fye, Gary
Kepko, Douglas
Kalayanamitra, Ricci
Shahid, Zainab
Ramgobin, Devyani
Cai, Alice
Groff, Andrew
Bhandari, Abani
Aggarwal, Chander Shekher
Patel, Ravi
Bhatt, Dhirisha
Polimera, Hyma
Sahu, Nitasa
Vunnam, Ramarao
Golamari, Reshma
Kumar, Ashutosh
Jain, Rohit
Approach to critical illness myopathy and polyneuropathy in the older SARS-CoV-2 patients
title Approach to critical illness myopathy and polyneuropathy in the older SARS-CoV-2 patients
title_full Approach to critical illness myopathy and polyneuropathy in the older SARS-CoV-2 patients
title_fullStr Approach to critical illness myopathy and polyneuropathy in the older SARS-CoV-2 patients
title_full_unstemmed Approach to critical illness myopathy and polyneuropathy in the older SARS-CoV-2 patients
title_short Approach to critical illness myopathy and polyneuropathy in the older SARS-CoV-2 patients
title_sort approach to critical illness myopathy and polyneuropathy in the older sars-cov-2 patients
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380205/
https://www.ncbi.nlm.nih.gov/pubmed/33070904
http://dx.doi.org/10.1016/j.jocn.2020.07.058
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