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A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2
The influenza virus hemagglutinin (HA) and coronavirus spike (S) protein mediate virus entry. HA and S proteins are heavily glycosylated, making them potential targets for carbohydrate binding agents such as lectins. Here, we show that the lectin FRIL, isolated from hyacinth beans (Lablab purpureus)...
Autores principales: | Liu, Yo-Min, Shahed-Al-Mahmud, Md., Chen, Xiaorui, Chen, Ting-Hua, Liao, Kuo-Shiang, Lo, Jennifer M., Wu, Yi-Min, Ho, Meng-Chiao, Wu, Chung-Yi, Wong, Chi-Huey, Jan, Jia-Tsrong, Ma, Che |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380208/ https://www.ncbi.nlm.nih.gov/pubmed/32755598 http://dx.doi.org/10.1016/j.celrep.2020.108016 |
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