Cargando…

Using Serum Metabolomics to Predict Development of Anti-drug Antibodies in Multiple Sclerosis Patients Treated With IFNβ

Background: Neutralizing anti-drug antibodies (ADA) can greatly reduce the efficacy of biopharmaceuticals used to treat patients with multiple sclerosis (MS). However, the biological factors pre-disposing an individual to develop ADA are poorly characterized. Thus, there is an unmet clinical need fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Waddington, Kirsty E., Papadaki, Artemis, Coelewij, Leda, Adriani, Marsilio, Nytrova, Petra, Kubala Havrdova, Eva, Fogdell-Hahn, Anna, Farrell, Rachel, Dönnes, Pierre, Pineda-Torra, Inés, Jury, Elizabeth C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380268/ https://www.ncbi.nlm.nih.gov/pubmed/32765529 http://dx.doi.org/10.3389/fimmu.2020.01527

Ejemplares similares

Disrupted Lipid Metabolism in Multiple Sclerosis: A Role for Liver X Receptors?
por: Pineda-Torra, Inés, et al.
Publicado: (2021)

Impact of immunogenicity on clinical efficacy and toxicity profile of biologic agents used for treatment of inflammatory arthritis in children compared to adults
por: Parikh, Chinar R., et al.
Publicado: (2021)

Disease-associated and patient-specific immune cell signatures in juvenile-onset systemic lupus erythematosus: patient stratification using a machine-learning approach
por: Robinson, George A, et al.
Publicado: (2020)

Increased apolipoprotein-B:A1 ratio predicts cardiometabolic risk in patients with juvenile onset SLE
por: Robinson, George A., et al.
Publicado: (2021)

Transcriptional Regulation of T-Cell Lipid Metabolism: Implications for Plasma Membrane Lipid Rafts and T-Cell Function
por: Robinson, George A., et al.
Publicado: (2017)

Predicting long-term cardiometabolic risk: Do childhood metabolomic signatures hold the key?
por: Robinson, George A, et al.
Publicado: (2021)

Metabolomics Defines Complex Patterns of Dyslipidaemia in Juvenile-SLE Patients Associated with Inflammation and Potential Cardiovascular Disease Risk
por: Robinson, George A., et al.
Publicado: (2021)

Lipid metabolism in autoimmune rheumatic disease: implications for modern and conventional therapies
por: Robinson, George, et al.
Publicado: (2022)

Challenges in Implementing Cardiovascular Risk Scores for Assessment of Young People With Childhood-Onset Autoimmune Rheumatic Conditions
por: Ciurtin, Coziana, et al.
Publicado: (2022)

Sex Differences in Lipid Metabolism: Implications for Systemic Lupus Erythematosus and Cardiovascular Disease Risk
por: Robinson, George A., et al.
Publicado: (2022)

CD8+ T-Cells in Juvenile-Onset SLE: From Pathogenesis to Comorbidities
por: Ciurtin, Coziana, et al.
Publicado: (2022)

Real-Life Outcome in Multiple Sclerosis in the Czech Republic
por: Kobelt, Gisela, et al.
Publicado: (2019)

Sex bias in multiple sclerosis and neuromyelitis optica spectrum disorders: How it influences clinical course, MRI parameters and prognosis
por: Nytrova, Petra, et al.
Publicado: (2022)

The potential of serum neurofilament as biomarker for multiple sclerosis
por: Bittner, Stefan, et al.
Publicado: (2021)

Machine Learning Techniques for Personalised Medicine Approaches in Immune-Mediated Chronic Inflammatory Diseases: Applications and Challenges
por: Peng, Junjie, et al.
Publicado: (2021)

Weighted Burden Analysis of Exome-Sequenced Case-Control Sample Implicates Synaptic Genes in Schizophrenia Aetiology
por: Curtis, David, et al.
Publicado: (2018)

Investigating sex differences in T regulatory cells from cisgender and transgender healthy individuals and patients with autoimmune inflammatory disease: a cross-sectional study
por: Robinson, George A, et al.
Publicado: (2022)

The nuclear receptor LXR modulates interleukin-18 levels in macrophages through multiple mechanisms
por: Pourcet, Benoit, et al.
Publicado: (2016)

The role of herpesvirus 6A and 6B in multiple sclerosis and epilepsy
por: Dunn, Nicky, et al.
Publicado: (2020)

Sex hormones drive changes in lipoprotein metabolism
por: Robinson, George A., et al.
Publicado: (2021)

Biofeedback Based Home Balance Training can Improve Balance but Not Gait in People with Multiple Sclerosis
por: Novotna, Klara, et al.
Publicado: (2019)

Effects of Menopause in Women With Multiple Sclerosis: An Evidence-Based Review
por: Bove, Riley, et al.
Publicado: (2021)

Natalizumab Induces Changes of Cerebrospinal Fluid Measures in Multiple Sclerosis
por: Ganapathy Subramanian, Ranjani, et al.
Publicado: (2021)

Do eyes with and without optic neuritis in multiple sclerosis age equally?
por: Lizrova Preiningerova, Jana, et al.
Publicado: (2018)

Myxovirus Resistance Protein A mRNA Expression Kinetics in Multiple Sclerosis Patients Treated with IFNβ
por: Libertinova, Jana, et al.
Publicado: (2017)

Corrigendum to ’To be or not to be vaccinated: The risk of MS or NMOSD relapse after COVID-19 vaccination and infection’[Multiple sclerosis and related disorders vol. 65 (2022) 104014]
por: Stastna, Dominika, et al.
Publicado: (2023)

Multiple Sclerosis and Microbiome
por: Preiningerova, Jana Lizrova, et al.
Publicado: (2022)

Long-Term Consequences of High Titer Neutralizing Antibodies to Interferon-β in Multiple Sclerosis
por: Dunn, Nicky, et al.
Publicado: (2020)

Flow Cytometry Analysis of Blood Large Extracellular Vesicles in Patients with Multiple Sclerosis Experiencing Relapse of the Disease
por: Soukup, Jakub, et al.
Publicado: (2022)

Steroid Sulfation in Neurodegenerative Diseases
por: Vitku, Jana, et al.
Publicado: (2022)

Editorial: Nuclear Receptors and Coregulators in Metabolism and Immunity
por: Fan, Rongrong, et al.
Publicado: (2021)

Critical appraisal of the role of fingolimod in the treatment of multiple sclerosis
por: Warnke, Clemens, et al.
Publicado: (2011)

Posttranslational Modifications of Lipid-Activated Nuclear Receptors: Focus on Metabolism
por: Becares, Natalia, et al.
Publicado: (2016)

Evolution of Brain Volume Loss Rates in Early Stages of Multiple Sclerosis
por: Uher, Tomas, et al.
Publicado: (2021)

Cognitive clinico‐radiological paradox in early stages of multiple sclerosis
por: Uher, Tomas, et al.
Publicado: (2017)

Deep Gray Matter Iron Content in Neuromyelitis Optica and Multiple Sclerosis
por: Pudlac, Adam, et al.
Publicado: (2020)

Editorial: Clinical management, pathogenesis and biomarkers of cardiovascular disease associated with systemic autoimmune disorders
por: Perez-Sanchez, Carlos, et al.
Publicado: (2022)

Long-term Treatment With Ponesimod in Relapsing-Remitting Multiple Sclerosis: Results From Randomized Phase 2b Core and Extension Studies
por: Freedman, Mark S., et al.
Publicado: (2022)

To be or not to be vaccinated: The risk of MS or NMOSD relapse after COVID-19 vaccination and infection
por: Stastna, Dominika, et al.
Publicado: (2022)

Modulatory effects on dendritic cells by human herpesvirus 6
por: Gustafsson, Rasmus, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_h977lsulroes7ausfhetm661bc