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PRMT5 function and targeting in cancer

Protein methyl transferases play critical roles in numerous regulatory pathways that underlie cancer development, progression and therapy-response. Here we discuss the function of PRMT5, a member of the nine-member PRMT family, in controlling oncogenic processes including tumor intrinsic, as well as...

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Detalles Bibliográficos
Autores principales: Kim, Hyungsoo, Ronai, Ze'ev A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380451/
https://www.ncbi.nlm.nih.gov/pubmed/32743345
http://dx.doi.org/10.15698/cst2020.08.228