Cargando…

Challenges faced in the management of complicated Boerhaave syndrome: a tertiary care center experience

Spontaneous esophageal perforation is rare and is associated with high morbidity and mortality. A spectrum of various surgical modalities ranging from primary surgical repair to esophagectomy is available for its management. The optimal management of patients presenting late in a hemodynamically sta...

Descripción completa

Detalles Bibliográficos
Autores principales: Harikrishnan, Sakthivel, Murugesan, Chandramohan Servarayan, Karthikeyan, Raveena, Manickavasagam, Kanagavel, Singh, Balaji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380874/
https://www.ncbi.nlm.nih.gov/pubmed/32754292
http://dx.doi.org/10.11604/pamj.2020.36.65.23666
_version_ 1783562928947986432
author Harikrishnan, Sakthivel
Murugesan, Chandramohan Servarayan
Karthikeyan, Raveena
Manickavasagam, Kanagavel
Singh, Balaji
author_facet Harikrishnan, Sakthivel
Murugesan, Chandramohan Servarayan
Karthikeyan, Raveena
Manickavasagam, Kanagavel
Singh, Balaji
author_sort Harikrishnan, Sakthivel
collection PubMed
description Spontaneous esophageal perforation is rare and is associated with high morbidity and mortality. A spectrum of various surgical modalities ranging from primary surgical repair to esophagectomy is available for its management. The optimal management of patients presenting late in a hemodynamically stable condition is not clearly defined in the literature. A retrospective review of all patients with Boerhaave syndrome managed by a single surgical team in a tertiary care center between 2008 and 2019 was performed (n = 16). Eleven patients were initially managed in the medical intensive care unit (MICU) as non-esophageal cause and 5 patients were referred after failed management (conservative/endoscopic). Demographics, clinical presentation, characteristics of perforation, initial diagnosis, and treatment were analyzed. All patients were males with a mean age of 42.2 years. A history of ethanol use was present in 6 patients. The median delay in diagnosis and referral was 16 days (range: 11-40 days). The common presenting symptoms were chest pain (n=11), dyspnoea (n=10), vomiting (n=4) and cough (n=2). The perforation was directed into right, left, and bilateral pleural cavities in 6, 8, and 2 patients respectively. The location of perforation was distal esophagus except for one patient. One patient was successfully treated with conservative management. The remaining patients underwent esophagectomy as a definitive surgical procedure. There was no significant postoperative morbidity and mortality. Esophagectomy can be done as a one-stage definitive procedure for patients with Boerhaave syndrome who present late in a hemodynamically stable condition with acceptable morbidity and good long term outcome.
format Online
Article
Text
id pubmed-7380874
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher The African Field Epidemiology Network
record_format MEDLINE/PubMed
spelling pubmed-73808742020-08-03 Challenges faced in the management of complicated Boerhaave syndrome: a tertiary care center experience Harikrishnan, Sakthivel Murugesan, Chandramohan Servarayan Karthikeyan, Raveena Manickavasagam, Kanagavel Singh, Balaji Pan Afr Med J Case Series Spontaneous esophageal perforation is rare and is associated with high morbidity and mortality. A spectrum of various surgical modalities ranging from primary surgical repair to esophagectomy is available for its management. The optimal management of patients presenting late in a hemodynamically stable condition is not clearly defined in the literature. A retrospective review of all patients with Boerhaave syndrome managed by a single surgical team in a tertiary care center between 2008 and 2019 was performed (n = 16). Eleven patients were initially managed in the medical intensive care unit (MICU) as non-esophageal cause and 5 patients were referred after failed management (conservative/endoscopic). Demographics, clinical presentation, characteristics of perforation, initial diagnosis, and treatment were analyzed. All patients were males with a mean age of 42.2 years. A history of ethanol use was present in 6 patients. The median delay in diagnosis and referral was 16 days (range: 11-40 days). The common presenting symptoms were chest pain (n=11), dyspnoea (n=10), vomiting (n=4) and cough (n=2). The perforation was directed into right, left, and bilateral pleural cavities in 6, 8, and 2 patients respectively. The location of perforation was distal esophagus except for one patient. One patient was successfully treated with conservative management. The remaining patients underwent esophagectomy as a definitive surgical procedure. There was no significant postoperative morbidity and mortality. Esophagectomy can be done as a one-stage definitive procedure for patients with Boerhaave syndrome who present late in a hemodynamically stable condition with acceptable morbidity and good long term outcome. The African Field Epidemiology Network 2020-06-03 /pmc/articles/PMC7380874/ /pubmed/32754292 http://dx.doi.org/10.11604/pamj.2020.36.65.23666 Text en © Sakthivel Harikrishnan et al. https://creativecommons.org/licenses/by/4.0 The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Series
Harikrishnan, Sakthivel
Murugesan, Chandramohan Servarayan
Karthikeyan, Raveena
Manickavasagam, Kanagavel
Singh, Balaji
Challenges faced in the management of complicated Boerhaave syndrome: a tertiary care center experience
title Challenges faced in the management of complicated Boerhaave syndrome: a tertiary care center experience
title_full Challenges faced in the management of complicated Boerhaave syndrome: a tertiary care center experience
title_fullStr Challenges faced in the management of complicated Boerhaave syndrome: a tertiary care center experience
title_full_unstemmed Challenges faced in the management of complicated Boerhaave syndrome: a tertiary care center experience
title_short Challenges faced in the management of complicated Boerhaave syndrome: a tertiary care center experience
title_sort challenges faced in the management of complicated boerhaave syndrome: a tertiary care center experience
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380874/
https://www.ncbi.nlm.nih.gov/pubmed/32754292
http://dx.doi.org/10.11604/pamj.2020.36.65.23666
work_keys_str_mv AT harikrishnansakthivel challengesfacedinthemanagementofcomplicatedboerhaavesyndromeatertiarycarecenterexperience
AT murugesanchandramohanservarayan challengesfacedinthemanagementofcomplicatedboerhaavesyndromeatertiarycarecenterexperience
AT karthikeyanraveena challengesfacedinthemanagementofcomplicatedboerhaavesyndromeatertiarycarecenterexperience
AT manickavasagamkanagavel challengesfacedinthemanagementofcomplicatedboerhaavesyndromeatertiarycarecenterexperience
AT singhbalaji challengesfacedinthemanagementofcomplicatedboerhaavesyndromeatertiarycarecenterexperience