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Exosomal lncRNA PCAT-1 promotes Kras-associated chemoresistance via immunosuppressive miR-182/miR-217 signaling and p27/CDK6 regulation
Immunosuppressive chemoresistance is a major burden in lung cancer. Recent data reveal that long noncoding RNAs (lncRNAs) present in the lung tumor microenvironment are implicated in chemoresistant-related immune deregulation, and metastasis but their exact pathogenic role is still unknown. In this...
Autores principales: | Domvri, Kalliopi, Petanidis, Savvas, Anestakis, Doxakis, Porpodis, Konstantinos, Bai, Chong, Zarogoulidis, Paul, Freitag, Lutz, Hohenforst-Schmidt, Wolfgang, Katopodi, Theodora |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381096/ https://www.ncbi.nlm.nih.gov/pubmed/32754302 http://dx.doi.org/10.18632/oncotarget.27675 |
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