Therapeutic efficacy of liposomal Grb2 antisense oligodeoxynucleotide (L-Grb2) in preclinical models of ovarian and uterine cancer

Background: Adaptor proteins such as growth factor receptor-bound protein-2 (Grb2) play important roles in cancer cell signaling. In the present study, we examined the biological effects of liposomal antisense oligodeoxynucleotide that blocks Grb2 expression (L-Grb2) in gynecologic cancer models. Ma...

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Detalles Bibliográficos
Autores principales: Lara, Olivia D., Bayraktar, Emine, Amero, Paola, Ma, Shaolin, Ivan, Cristina, Hu, Wei, Wang, Ying, Mangala, Lingegowda S., Dutta, Prasanta, Bhattacharya, Pratip, Ashizawa, Ana Tari, Lopez-Berestein, Gabriel, Rodriguez-Aguayo, Cristian, Sood, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381098/
https://www.ncbi.nlm.nih.gov/pubmed/32754300
http://dx.doi.org/10.18632/oncotarget.27667

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