Cargando…

ZFP36 Binds With PRC1 to Inhibit Tumor Growth and Increase 5-Fu Chemosensitivity of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is the fifth common cause of tumor-related death worldwide. ZFP36, a RNA-binding protein, decreases in many cancers and its role in HCC remains unclear. This study aimed to investigate the underlying mechanisms by which ZFP36 inhibited HCC progression and increased flu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Weiqian, Chen, Minjiang, Zhao, Zhongwei, Weng, Qiaoyou, Song, Jingjing, Fang, Shiji, Wu, Xulu, Wang, Hailin, Zhang, Dengke, Yang, Weibin, Wang, Zufei, Xu, Min, Ji, Jiansong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381195/ https://www.ncbi.nlm.nih.gov/pubmed/32766276 http://dx.doi.org/10.3389/fmolb.2020.00126

Ejemplares similares

Efficacy and Safety of TACE Combined With Sorafenib Plus Immune Checkpoint Inhibitors for the Treatment of Intermediate and Advanced TACE-Refractory Hepatocellular Carcinoma: A Retrospective Study
por: Zheng, Liyun, et al.
Publicado: (2021)

A Radiomics Signature-Based Nomogram to Predict the Progression-Free Survival of Patients With Hepatocellular Carcinoma After Transcatheter Arterial Chemoembolization Plus Radiofrequency Ablation
por: Fang, Shiji, et al.
Publicado: (2021)

CPEB1 mediates hepatocellular carcinoma cancer stemness and chemoresistance
por: Xu, Min, et al.
Publicado: (2018)

Triptonide Modulates MAPK Signaling Pathways and Exerts Anticancer Effects via ER Stress-Mediated Apoptosis Induction in Human Osteosarcoma Cells
por: Zheng, Liyun, et al.
Publicado: (2020)

TACE responser NDRG1 acts as a guardian against ferroptosis to drive tumorgenesis and metastasis in HCC
por: Tang, Bufu, et al.
Publicado: (2023)

Targeted xCT‐mediated Ferroptosis and Protumoral Polarization of Macrophages Is Effective against HCC and Enhances the Efficacy of the Anti‐PD‐1/L1 Response
por: Tang, Bufu, et al.
Publicado: (2022)

Changes in hepatic metabolic profile during the evolution of STZ-induced diabetic rats via an (1)H NMR-based metabonomic investigation
por: Chen, Minjiang, et al.
Publicado: (2019)

Precision interventional radiology
por: Ji, Jiansong, et al.
Publicado: (2021)

Conflicting Roles of ZFP36L1 in Regulating the Progression of Muscle Invasive Bladder Cancer
por: Yuan, Simin, et al.
Publicado: (2022)

The Effect of m6A Methylation Regulatory Factors on the Malignant Progression and Clinical Prognosis of Hepatocellular Carcinoma
por: Zhao, Zhongwei, et al.
Publicado: (2020)

miR-590-5p suppresses hepatocellular carcinoma chemoresistance by targeting YAP1 expression
por: Chen, Minjiang, et al.
Publicado: (2018)

Piperlongumine, a Novel TrxR1 Inhibitor, Induces Apoptosis in Hepatocellular Carcinoma Cells by ROS-Mediated ER Stress
por: Zhang, Qianqian, et al.
Publicado: (2019)

Corrigendum: Piperlongumine, a Novel TrxR1 Inhibitor, Induces Apoptosis in Hepatocellular Carcinoma Cells by ROS-Mediated ER Stress
por: Zhang, Qianqian, et al.
Publicado: (2022)

(125)I brachytherapy of locally advanced non-small-cell lung cancer after one cycle of first-line chemotherapy: a comparison with best supportive care
por: Song, Jingjing, et al.
Publicado: (2017)

Prediction of tumor response via a pretreatment MRI radiomics-based nomogram in HCC treated with TACE
por: Kong, Chunli, et al.
Publicado: (2021)

Predictive Models for HCC Prognosis, Recurrence Risk, and Immune Infiltration Based on Two Exosomal Genes: MYL6B and THOC2
por: Zhu, Jinyu, et al.
Publicado: (2021)

Radiomic Feature-Based Nomogram: A Novel Technique to Predict EGFR-Activating Mutations for EGFR Tyrosin Kinase Inhibitor Therapy
por: Weng, Qiaoyou, et al.
Publicado: (2021)

Predictive Models for Colon Adenocarcinoma Diagnosis, Prognosis, and Immune Microenvironment Based on 2 Hypoxia-Related Genes: KDM3A and ENO3
por: Kong, Chunli, et al.
Publicado: (2023)

Multi-algorithms analysis for pre-treatment prediction of response to transarterial chemoembolization in hepatocellular carcinoma on multiphase MRI
por: Chen, Mingzhen, et al.
Publicado: (2023)

CircSOD2 induced epigenetic alteration drives hepatocellular carcinoma progression through activating JAK2/STAT3 signaling pathway
por: Zhao, Zhongwei, et al.
Publicado: (2020)

High expression of angiogenic factor AGGF1 is an independent prognostic factor for hepatocellular carcinoma
por: Tu, Jianfei, et al.
Publicado: (2017)

Precise prediction of the sensitivity of platinum chemotherapy in SCLC: Establishing and verifying the feasibility of a CT-based radiomics nomogram
por: Su, Yanping, et al.
Publicado: (2023)

SMYD3 associates with the NuRD (MTA1/2) complex to regulate transcription and promote proliferation and invasiveness in hepatocellular carcinoma cells
por: Yang, Yang, et al.
Publicado: (2022)

Therapeutic Potential of Triptolide as an Anti-Inflammatory Agent in Dextran Sulfate Sodium-Induced Murine Experimental Colitis
por: Tang, Bufu, et al.
Publicado: (2020)

The RNA-binding proteins Zfp36l1 and Zfp36l2 act redundantly in myogenesis
por: Bye-A-Jee, Hema, et al.
Publicado: (2018)

MLL4 Regulates the Progression of Non–Small-Cell Lung Cancer by Regulating the PI3K/AKT/SOX2 Axis
por: Yang, Yang, et al.
Publicado: (2023)

A role for the NPM1/PTPN14/YAP axis in mediating hypoxia-induced chemoresistance to sorafenib in hepatocellular carcinoma
por: Zhang, Dengke, et al.
Publicado: (2022)

Identification of the Potential Metabolic Pathways Involved in the Hepatic Tumorigenesis of Rat Diethylnitrosamine-Induced Hepatocellular Carcinoma via (1)H NMR-Based Metabolomic Analysis
por: Chen, Minjiang, et al.
Publicado: (2019)

Selective killing of gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress activation
por: Chen, Weiqian, et al.
Publicado: (2016)

Correction to: Integrated analysis reveals critical glycolytic regulators in hepatocellular carcinoma
por: Lu, Chenying, et al.
Publicado: (2020)

Integrated analysis reveals critical glycolytic regulators in hepatocellular carcinoma
por: Lu, Chenying, et al.
Publicado: (2020)

Shikonin potentiates the effect of arsenic trioxide against human hepatocellular carcinoma in vitro and in vivo
por: Song, Jingjing, et al.
Publicado: (2016)

ZFP36L1 and ZFP36L2 inhibit cell proliferation in a cyclin D-dependent and p53-independent manner
por: Suk, Fat-Moon, et al.
Publicado: (2018)

ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK–RSK pathway
por: Adachi, Shungo, et al.
Publicado: (2014)

Functional regulation of Zfp36l1 and Zfp36l2 in response to lipopolysaccharide in mouse RAW264.7 macrophages
por: Wang, Kuan-Ting, et al.
Publicado: (2015)

Knockout of SIRT4 decreases chemosensitivity to 5-FU in colorectal cancer cells
por: Zhu, Yuanyuan, et al.
Publicado: (2018)

Orthotopic hepatocellular carcinoma: molecular imaging-monitored intratumoral hyperthermia-enhanced direct oncolytic virotherapy
por: Song, Jingjing, et al.
Publicado: (2019)

ZFP36L2 Role in Thyroid Functionality
por: Albano, Francesco, et al.
Publicado: (2021)

Circular RNA Circ0021205 Promotes Cholangiocarcinoma Progression Through MiR-204-5p/RAB22A Axis
por: Tu, Jianfei, et al.
Publicado: (2021)

Delivery strategies of cancer immunotherapy: recent advances and future perspectives
por: Zhao, Zhongwei, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_jo3t259t1jke6bdnlguag8v0m1