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In and Out of the Bursa—The Role of CXCR4 in Chicken B Cell Development

In contrast to mammals, early B cell differentiation and diversification of the antibody repertoire in chickens do not take place in the bone marrow but in a specialized gut associated lymphoid tissue (GALT), the bursa of Fabricius. During embryonic development, B cell precursors migrate to the burs...

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Detalles Bibliográficos
Autores principales: Nagy, Nandor, Busalt, Florian, Halasy, Viktoria, Kohn, Marina, Schmieder, Stefan, Fejszak, Nora, Kaspers, Bernd, Härtle, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381227/
https://www.ncbi.nlm.nih.gov/pubmed/32765509
http://dx.doi.org/10.3389/fimmu.2020.01468