Nicotine Changes the microRNA Profile to Regulate the FOXO Memory Program of CD8(+) T Cells in Rheumatoid Arthritis

Objective: Smoking suppresses PD-1 expression in patients with rheumatoid arthritis (RA). In this study, we assess if smoking changed the epigenetic control over CD8(+) T cell memory formation through a microRNA (miR) dependent mechanism. Methods: Phenotypes of CD8(+) T cells from smokers and non-sm...

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Detalles Bibliográficos
Autores principales: Wasén, Caroline, Ospelt, Caroline, Camponeschi, Alessandro, Erlandsson, Malin C., Andersson, Karin M. E., Silfverswärd, Sofia Töyrä, Gay, Steffen, Bokarewa, Maria I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381249/
https://www.ncbi.nlm.nih.gov/pubmed/32765511
http://dx.doi.org/10.3389/fimmu.2020.01474

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