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A Bromodomain-Containing Protein 4 (BRD4) Inhibitor Suppresses Angiogenesis by Regulating AP-1 Expression

Angiogenesis dysregulation contributes to inflammation, infections, immune disorders, and carcinogenesis. Bromodomain-containing protein 4 (BRD4) is an epigenetic reader that recognizes histone proteins and acts as a transcriptional regulator to trigger tumor growth and the inflammatory response. Th...

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Detalles Bibliográficos
Autores principales: Zhou, Zijun, Li, Xiaoming, Liu, Zhiqing, Huang, Lixun, Yao, Yuying, Li, Liuyou, Chen, Jian, Zhang, Rongxin, Zhou, Jia, Wang, Lijing, Zhang, Qian-Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381267/
https://www.ncbi.nlm.nih.gov/pubmed/32765266
http://dx.doi.org/10.3389/fphar.2020.01043