Cargando…

B Cell Therapy in Systemic Lupus Erythematosus: From Rationale to Clinical Practice

B cell hyperactivity and breach of tolerance constitute hallmarks of systemic lupus erythematosus (SLE). The heterogeneity of disease manifestations and relatively rare prevalence of SLE have posed difficulties in trial design and contributed to a slow pace for drug development. The anti-BAFF monocl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Parodis, Ioannis, Stockfelt, Marit, Sjöwall, Christopher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381321/ https://www.ncbi.nlm.nih.gov/pubmed/32754605 http://dx.doi.org/10.3389/fmed.2020.00316

Ejemplares similares

B cells in systemic lupus erythematosus: Targets of new therapies and surveillance tools
por: Parodis, Ioannis, et al.
Publicado: (2022)

Clinical Heterogeneity, Unmet Needs and Long-Term Outcomes in Patients with Systemic Lupus Erythematosus
por: Sjöwall, Christopher, et al.
Publicado: (2022)

Janus kinase inhibitors in systemic lupus erythematosus: implications for tyrosine kinase 2 inhibition
por: Nikolopoulos, Dionysis, et al.
Publicado: (2023)

B Cell Kinetics upon Therapy Commencement for Active Extrarenal Systemic Lupus Erythematosus in Relation to Development of Renal Flares: Results from Three Phase III Clinical Trials of Belimumab
por: Parodis, Ioannis, et al.
Publicado: (2022)

Early Changes in B and Plasma Cell Subsets and Traditional Serological Markers as Predictors of SRI-4 Response to Therapy in Systemic Lupus Erythematosus
por: Parodis, Ioannis, et al.
Publicado: (2022)

Obesity is associated with pain and impaired mobility despite therapy in systemic lupus erythematosus
por: Borg, Alexander, et al.
Publicado: (2023)

Adverse Health-Related Quality of Life Outcome Despite Adequate Clinical Response to Treatment in Systemic Lupus Erythematosus
por: Gomez, Alvaro, et al.
Publicado: (2021)

Impaired Microcirculation and Vascular Hemodynamics in Relation to Macrocirculation in Patients With Systemic Lupus Erythematosus
por: Svensson, Christina, et al.
Publicado: (2021)

Autoantibody and Cytokine Profiles during Treatment with Belimumab in Patients with Systemic Lupus Erythematosus
por: Parodis, Ioannis, et al.
Publicado: (2020)

Patient-Reported Outcomes in Systemic Lupus Erythematosus. Can Lupus Patients Take the Driver’s Seat in Their Disease Monitoring?
por: Parodis, Ioannis, et al.
Publicado: (2022)

EQ-5D full health state after therapy heralds reduced hazard to accrue subsequent organ damage in systemic lupus erythematosus
por: Lindblom, Julius, et al.
Publicado: (2022)

Increased levels of anti-dsDNA antibodies in immune complexes before treatment with belimumab associate with clinical response in patients with systemic lupus erythematosus
por: Sohrabian, Azita, et al.
Publicado: (2019)

Impact of Belimumab on Patient-Reported Outcomes in Systemic Lupus Erythematosus: Insights from Clinical Trials and Real-World Evidence
por: Gomez, Alvaro, et al.
Publicado: (2023)

Clinical Experience of Sirolimus Regarding Efficacy and Safety in Systemic Lupus Erythematosus
por: Eriksson, Per, et al.
Publicado: (2019)

High-Frequency Ultrasound of Multiple Arterial Areas Reveals Increased Intima Media Thickness, Vessel Wall Appearance, and Atherosclerotic Plaques in Systemic Lupus Erythematosus
por: Svensson, Christina, et al.
Publicado: (2020)

Longitudinal Analysis of Anti-cardiolipin and Anti-β2-glycoprotein-I Antibodies in Recent-Onset Systemic Lupus Erythematosus: A Prospective Study in Swedish Patients
por: Frodlund, Martina, et al.
Publicado: (2021)

Fatigue in Systemic Lupus Erythematosus and Rheumatoid Arthritis: A Comparison of Mechanisms, Measures and Management
por: Dey, Mrinalini, et al.
Publicado: (2021)

Biomarkers in Neuropsychiatric Systemic Lupus Erythematosus: A Systematic Literature Review of the Last Decade
por: Lindblom, Julius, et al.
Publicado: (2022)

Predictors of low disease activity and clinical remission following belimumab treatment in systemic lupus erythematosus
por: Parodis, Ioannis, et al.
Publicado: (2019)

Emerging Therapies in Cutaneous Lupus Erythematosus
por: Sprow, Grant, et al.
Publicado: (2022)

Application of the 2012 Systemic Lupus International Collaborating Clinics classification criteria to patients in a regional Swedish systemic lupus erythematosus register
por: Ighe, Anna, et al.
Publicado: (2015)

NET Formation in Systemic Lupus Erythematosus: Changes during the COVID-19 Pandemic
por: Knopf, Jasmin, et al.
Publicado: (2022)

How Can We Enhance Adherence to Medications in Patients with Systemic Lupus Erythematosus? Results from a Qualitative Study
por: Emamikia, Sharzad, et al.
Publicado: (2022)

Role of autotaxin in systemic lupus erythematosus
por: Tsuchida, Yumi, et al.
Publicado: (2023)

Clinical aspects of cutaneous lupus erythematosus
por: Elmgren, Julia, et al.
Publicado: (2023)

Editorial: Lupus and the Brain: Advances in Neuropsychiatric Systemic Lupus Erythematosus
por: Fanouriakis, Antonis, et al.
Publicado: (2019)

Systemic Lupus Erythematosus in Primary Care: An Update and Practical Messages for the General Practitioner
por: Gergianaki, Irini, et al.
Publicado: (2018)

Perihepatitis in systemic lupus erythematosus
por: Laabidi, Janet, et al.
Publicado: (2015)

Fighting Fatigue in Systemic Lupus Erythematosus: Experience of Dehydroepiandrosterone on Clinical Parameters and Patient-Reported Outcomes
por: Skoglund, Oliver, et al.
Publicado: (2022)

COVID-19 vaccine safety during pregnancy in women with systemic lupus erythematosus
por: Giannopoulou, Nefeli, et al.
Publicado: (2023)

Lupus and the Lungs: The Assessment and Management of Pulmonary Manifestations of Systemic Lupus Erythematosus
por: Amarnani, Raj, et al.
Publicado: (2021)

Attribution of Neuropsychiatric Manifestations to Systemic Lupus Erythematosus
por: Bortoluzzi, Alessandra, et al.
Publicado: (2018)

Novel Insights in Systemic Lupus Erythematosus and Atherosclerosis
por: Teixeira, Vítor, et al.
Publicado: (2018)

What's New in the Treatment of Systemic Lupus Erythematosus
por: Liossis, Stamatis Nick, et al.
Publicado: (2021)

Sex hormones affect the pathogenesis and clinical characteristics of systemic lupus erythematosus
por: Kim, Ji-Won, et al.
Publicado: (2022)

Gut Microbiota in Systemic Lupus Erythematosus and Correlation With Diet and Clinical Manifestations
por: Wang, Xiao, et al.
Publicado: (2022)

Sex differences in clinical presentation of systemic lupus erythematosus
por: Ramírez Sepúlveda, Jorge I., et al.
Publicado: (2019)

Use of Antimalarial Agents Is Associated with Favourable Physical Functioning in Patients with Systemic Lupus Erythematosus
por: Gomez, Alvaro, et al.
Publicado: (2020)

The Complex Role of C-Reactive Protein in Systemic Lupus Erythematosus
por: Enocsson, Helena, et al.
Publicado: (2021)

Intracranial Calcifications in Systemic Lupus Erythematosus
por: Bhardwaj, Arshia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tiouigtmq5ggimk8h0pd6d723o