Cargando…

Peripherally induced brain tissue-resident memory CD8(+) T cells mediate protection against CNS infection

The central nervous system (CNS) is classically viewed as immune-privileged; however, recent advances highlight interactions between the peripheral immune system and CNS in controlling infections and tissue homeostasis. Tissue-resident memory (Trm) CD8(+) T cells in the CNS are generated after brain...

Descripción completa

Detalles Bibliográficos
Autores principales:	Urban, Stina L., Jensen, Isaac J., Shan, Qiang, Pewe, Lecia L., Xue, Hai-Hui, Badovinac, Vladimir P., Harty, John T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381383/ https://www.ncbi.nlm.nih.gov/pubmed/32572242 http://dx.doi.org/10.1038/s41590-020-0711-8

Ejemplares similares

Expeditious recruitment of circulating memory CD8 T cells to the liver facilitates control of malaria
por: Lefebvre, Mitchell N., et al.
Publicado: (2021)

In vivo CD8+ T Cell Dynamics in the Liver of Plasmodium yoelii Immunized and Infected Mice
por: Cabrera, Mynthia, et al.
Publicado: (2013)

Suppression of autoimmune demyelinating disease by preferential stimulation of CNS-specific CD8 T cells using Listeria-encoded neuroantigen
por: Itani, Farah R., et al.
Publicado: (2017)

Polymicrobial sepsis impairs bystander recruitment of effector cells to infected skin despite optimal sensing and alarming function of skin resident memory CD8 T cells
por: Danahy, Derek B., et al.
Publicado: (2017)

Protective function and durability of mouse lymph node-resident memory CD8(+) T cells
por: Anthony, Scott M, et al.
Publicado: (2021)

Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection
por: Schmidt, Megan E., et al.
Publicado: (2018)

Phenotypic and Functional Alterations in Circulating Memory CD8 T Cells with Time after Primary Infection
por: Martin, Matthew D., et al.
Publicado: (2015)

Therapeutic intervention in relapsing autoimmune demyelinating disease through induction of myelin-specific regulatory CD8 T cell responses
por: Brate, Ashley A., et al.
Publicado: (2019)

Time and Antigen-Stimulation History Influence Memory CD8 T Cell Bystander Responses
por: Martin, Matthew D., et al.
Publicado: (2017)

Defining Memory CD8 T Cell
por: Martin, Matthew D., et al.
Publicado: (2018)

Sepsis leads to lasting changes in phenotype and function of memory CD8 T cells
por: Jensen, Isaac J, et al.
Publicado: (2021)

Differential Role of “Signal 3” Inflammatory Cytokines in Regulating CD8 T Cell Expansion and Differentiation in vivo
por: Pham, Nhat-Long L., et al.
Publicado: (2011)

Pathogenic Role for Virus-Specific CD4 T Cells in Mice with Coronavirus-Induced Acute Encephalitis
por: Anghelina, Daniela, et al.
Publicado: (2006)

Predicting CD62L expression during the CD8+ T cell response in vivo
por: Schlub, Timothy E., et al.
Publicado: (2009)

Sepsis leads to lasting changes in phenotype and function of naïve CD8 T cells
por: Berton, Roger R., et al.
Publicado: (2023)

Tcf1 preprograms the mobilization of glycolysis in central memory CD8(+) T cells during recall responses
por: Shan, Qiang, et al.
Publicado: (2022)

Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross
por: Martin, Matthew D., et al.
Publicado: (2020)

Resident Memory-like CD8(+) T Cells Are Involved in Chronic Inflammatory and Neurodegenerative Diseases in the CNS
por: Kimura, Kimitoshi, et al.
Publicado: (2023)

Extreme CD8 T Cell Requirements for Anti-Malarial Liver-Stage Immunity following Immunization with Radiation Attenuated Sporozoites
por: Schmidt, Nathan W., et al.
Publicado: (2010)

The Timing of Stimulation and IL-2 Signaling Regulate Secondary CD8 T Cell Responses
por: Khan, Shaniya H., et al.
Publicado: (2015)

Sepsis-induced changes in differentiation, maintenance, and function of memory CD8 T cell subsets
por: Heidarian, Mohammad, et al.
Publicado: (2023)

Antigen-dependent and –independent contributions to primary memory CD8 T cell activation and protection following infection
por: Martin, Matthew D., et al.
Publicado: (2015)

Development of transgenic mice expressing a coronavirus-specific public CD4 T cell receptor
por: Zhao, Jingxian, et al.
Publicado: (2013)

Antigen Exposure History Defines CD8 T Cell Dynamics and Protection during Localized Pulmonary Infections
por: Van Braeckel-Budimir, Natalija, et al.
Publicado: (2017)

Revealing the Complexity in CD8 T Cell Responses to Infection in Inbred C57B/6 versus Outbred Swiss Mice
por: Martin, Matthew D., et al.
Publicado: (2017)

Impact of Inflammatory Cytokines on Effector and Memory CD8+ T Cells
por: Kim, Marie T., et al.
Publicado: (2014)

Secondary memory CD8(+) T cells are more protective but slower to acquire a central–memory phenotype
por: Jabbari, Ali, et al.
Publicado: (2006)

Inflammation Controls Susceptibility of Immune-Experienced Mice to Sepsis
por: Berton, Roger R., et al.
Publicado: (2022)

Influenza-Induced CD103(+) T Resident Memory Cells Exhibit Enhanced Functional Avidity over CD103(−) Memory T Cells in the Mediastinal Lymph Node
por: Crooks, Sequoia D., et al.
Publicado: (2022)

Peripheral and systemic antigens elicit an expandable pool of resident memory CD8(+) T cells in the bone marrow
por: Pascutti, Maria Fernanda, et al.
Publicado: (2019)

Incomplete Memories: The Natural Suppression of Tissue-Resident Memory CD8 T Cells in the Lung
por: Reagin, Katie L., et al.
Publicado: (2018)

Therapeutic PD-L1 and LAG-3 blockade rapidly clears established blood-stage Plasmodium infection
por: Butler, Noah S., et al.
Publicado: (2011)

CD8(+) Resident Memory T Cells and Viral Infection
por: Wu, Xuejie, et al.
Publicado: (2018)

Murine encephalitis caused by HCoV-OC43, a human coronavirus with broad species specificity, is partly immune-mediated
por: Butler, Noah, et al.
Publicado: (2006)

HCoV-OC43–Induced Encephalitis is in Part Immune-Mediated
por: Butler, Noah, et al.
Publicado: (2006)

Local Antigen Encounter Is Essential for Establishing Persistent CD8(+) T-Cell Memory in the CNS
por: Schøller, Amalie S., et al.
Publicado: (2019)

Runx3 guards cytotoxic CD8(+) effector T cells against deviation towards T(FH) cell lineage
por: Shan, Qiang, et al.
Publicado: (2017)

Sensing and alarm function of resident memory CD8(+) T cells
por: Schenkel, Jason M., et al.
Publicado: (2013)

Local immunity by tissue-resident CD8(+) memory T cells
por: Gebhardt, Thomas, et al.
Publicado: (2012)

Discipline in Stages: Regulating CD8(+) Resident Memory T Cells
por: Mora-Buch, Rut, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hf0pkhjtjmrvppr1qlmdkfm4lm