NOD2 Deficiency Promotes Intestinal CD4+ T Lymphocyte Imbalance, Metainflammation, and Aggravates Type 2 Diabetes in Murine Model

Type 2 diabetes (T2D) is a metabolic disease characterized by increased inflammation, NOD-like receptors (NLRs) activation and gut dysbiosis. Our research group has recently reported that intestinal Th17 response limits gut dysbiosis and LPS translocation to visceral adipose tissue (VAT), protecting...

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Detalles Bibliográficos
Autores principales: Carlos, Daniela, Pérez, Malena M., Leite, Jefferson A., Rocha, Fernanda A., Martins, Larissa M. S., Pereira, Camila A., Fraga-Silva, Thais F. C., Pucci, Taís A., Ramos, Simone G., Câmara, Niels O. S., Bonato, Vânia L. D., Tostes, Rita C., Silva, João S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381387/
https://www.ncbi.nlm.nih.gov/pubmed/32774333
http://dx.doi.org/10.3389/fimmu.2020.01265

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