S1P lyase inhibition protects against sepsis by promoting disease tolerance via the S1P/S1PR3 axis

BACKGROUND: One-third of all deaths in hospitals are caused by sepsis. Despite its demonstrated prevalence and high case fatality rate, antibiotics remain the only target-oriented treatment option currently available. Starting from results showing that low-dose anthracyclines protect against sepsis...

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Detalles Bibliográficos
Autores principales: Weigel, Cynthia, Hüttner, Sören S., Ludwig, Kristin, Krieg, Nadine, Hofmann, Susann, Schröder, Nathalie H., Robbe, Linda, Kluge, Stefan, Nierhaus, Axel, Winkler, Martin S., Rubio, Ignacio, von Maltzahn, Julia, Spiegel, Sarah, Gräler, Markus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381498/
https://www.ncbi.nlm.nih.gov/pubmed/32711251
http://dx.doi.org/10.1016/j.ebiom.2020.102898

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