Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity

Obesity is associated with low-grade chronic inflammation promoting insulin-resistance and diabetes. Gut microbiota dysbiosis is a consequence as well as a driver of obesity and diabetes. Mucosal-associated invariant T cells (MAIT) are innate-like T cells expressing a semi-invariant T cell receptor...

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Detalles Bibliográficos
Autores principales: Toubal, Amine, Kiaf, Badr, Beaudoin, Lucie, Cagninacci, Lucie, Rhimi, Moez, Fruchet, Blandine, da Silva, Jennifer, Corbett, Alexandra J., Simoni, Yannick, Lantz, Olivier, Rossjohn, Jamie, McCluskey, James, Lesnik, Philippe, Maguin, Emmanuelle, Lehuen, Agnès
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381641/
https://www.ncbi.nlm.nih.gov/pubmed/32709874
http://dx.doi.org/10.1038/s41467-020-17307-0

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