Subnanometer-resolution structure determination in situ by hybrid subtomogram averaging - single particle cryo-EM

Cryo-electron tomography combined with subtomogram averaging (StA) has yielded high-resolution structures of macromolecules in their native context. However, high-resolution StA is not commonplace due to beam-induced sample drift, images with poor signal-to-noise ratios (SNR), challenges in CTF corr...

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Detalles Bibliográficos
Autores principales: Sanchez, Ricardo M., Zhang, Yingyi, Chen, Wenbo, Dietrich, Lea, Kudryashev, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381653/
https://www.ncbi.nlm.nih.gov/pubmed/32709843
http://dx.doi.org/10.1038/s41467-020-17466-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381653/
https://www.ncbi.nlm.nih.gov/pubmed/32709843
http://dx.doi.org/10.1038/s41467-020-17466-0

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