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Stochastic master equation for early protein aggregation in the transthyretin amyloid disease

It is significant to understand the earliest molecular events occurring in the nucleation of the amyloid aggregation cascade for the prevention of amyloid related diseases such as transthyretin amyloid disease. We develop chemical master equation for the aggregation of monomers into oligomers using...

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Detalles Bibliográficos
Autores principales: Liu, Ruo-Nan, Kang, Yan-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381670/
https://www.ncbi.nlm.nih.gov/pubmed/32709875
http://dx.doi.org/10.1038/s41598-020-69319-x