ATF6 aggravates acinar cell apoptosis and injury by regulating p53/AIFM2 transcription in Severe Acute Pancreatitis

Background: There is no curative therapy for severe acute pancreatitis (SAP) due to poor understanding of its molecular mechanisms. Endoplasmic reticulum (ER) stress is involved in SAP and increased expression of ATF6 has been detected in SAP patients. Here, we aimed to investigate the role of ATF6...

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Detalles Bibliográficos
Autores principales: Tan, Jie-Hui, Cao, Rong-Chang, Zhou, Lei, Zhou, Zhi-Tao, Chen, Huo-Ji, Xu, Jia, Chen, Xue-Mei, Jin, Yang-Chen, Lin, Jia-Yu, Zeng, Jun-Ling, Li, Shu-Ji, Luo, Min, Hu, Guo-Dong, Yang, Xiao-Bing, Jin, Jin, Zhang, Guo-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381726/
https://www.ncbi.nlm.nih.gov/pubmed/32724472
http://dx.doi.org/10.7150/thno.46934

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