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Evaluation of (18)F-IAM6067 as a sigma-1 receptor PET tracer for neurodegeneration in vivo in rodents and in human tissue

The sigma 1 receptor (S1R) is widely expressed in the CNS and is mainly located on the endoplasmic reticulum. The S1R is involved in the regulation of many neurotransmission systems and, indirectly, in neurodegenerative diseases. The S1R may therefore represent an interesting neuronal biomarker in n...

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Detalles Bibliográficos
Autores principales:	Lepelletier, François-Xavier, Vandesquille, Matthias, Asselin, Marie-Claude, Prenant, Christian, Robinson, Andrew C, Mann, David M A, Green, Michael, Barnett, Elizabeth, Banister, Samuel D, Mottinelli, Marco, Mesangeau, Christophe, McCurdy, Christopher R, Fricke, Inga B, Jacobs, Andreas H., Kassiou, Michael, Boutin, Hervé
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381740/ https://www.ncbi.nlm.nih.gov/pubmed/32724451 http://dx.doi.org/10.7150/thno.47585

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