Neuroprotective Effect of Mesenchymal Stromal Cell-Derived Extracellular Vesicles Against Cerebral Ischemia-Reperfusion-Induced Neural Functional Injury: A Pivotal Role for AMPK and JAK2/STAT3/NF-κB Signaling Pathway Modulation

INTRODUCTION: Cerebral ischemia-reperfusion injury (CIRI) is the main factor that leads to poor prognosis of cerebral ischemia. Apoptosis has been shown to occur during the process of CIRI. Extracellular vesicles derived from mesenchymal stromal cells (MSCs-EVs) have shown broad potential for treati...

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Detalles Bibliográficos
Autores principales: Han, Min, Cao, Ying, Xue, Hao, Chu, Xili, Li, Tingting, Xin, Danqing, Yuan, Lin, Ke, Hongfei, Li, Gang, Wang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381771/
https://www.ncbi.nlm.nih.gov/pubmed/32764885
http://dx.doi.org/10.2147/DDDT.S248892

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