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The Regulating Mechanism of Chrysophanol on Protein Level of CaM-CaMKIV to Protect PC12 Cells Against Aβ(25-35)-Induced Damage

OBJECTIVE: To investigate the neuroprotective effect of chrysophanol (CHR) on PC12 treated with Aβ(25-35), and the involved mechanism. METHODS: After the establishment of an AD cell model induced by Aβ(25-35), the cell survival rate was detected by MTT, cell apoptosis was assayed by Hoechst 33342 st...

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Detalles Bibliográficos
Autores principales:	Ye, Ting, Gao, Hua-Wu, Xuan, Wei-Ting, Ye, Shu, Zhou, Peng, Li, Xin-Quan, Wang, Yan, Song, Hang, Liu, Yan-Yan, Cai, Biao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381772/ https://www.ncbi.nlm.nih.gov/pubmed/32764873 http://dx.doi.org/10.2147/DDDT.S245128

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