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Pristimerin Inhibits MMP-9 Expression and Cell Migration Through Attenuating NOX/ROS-Dependent NF-κB Activation in Rat Brain Astrocytes Challenged with LPS

PURPOSE: Neuroinflammation plays a crucial role in neurodegenerative diseases. Matrix metalloproteinases (MMPs) are a landmark of neuroinflammation. Lipopolysaccharide (LPS) has been demonstrated to induce MMP-9 expression. The mechanisms underlying LPS-induced MMP-9 expression have not been complet...

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Detalles Bibliográficos
Autores principales:	Yang, Chien-Chung, Hsiao, Li-Der, Tseng, Hui-Ching, Kuo, Ching-Ming, Yang, Chuen-Mao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381777/ https://www.ncbi.nlm.nih.gov/pubmed/32765041 http://dx.doi.org/10.2147/JIR.S252659

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