Cargando…
Preoperative Ultra-Short-Course Chemotherapy Combined with Surgery for the Treatment of Chest Wall Tuberculosis
OBJECTIVE: To investigate the safety and efficacy of preoperative ultra-short-course chemotherapy, combined with surgical treatment for chest wall tuberculosis and summarize our experience in this regard, to provide a reference for national and international clinicians. METHODS: A retrospective anal...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381815/ https://www.ncbi.nlm.nih.gov/pubmed/32765003 http://dx.doi.org/10.2147/IDR.S255740 |
_version_ | 1783563124772700160 |
---|---|
author | Zhang, Weidong Chen, Jingfang Wu, Xiaoming Chen, Luyu Wei, Jinxing Xue, Mingqiang Liu, Yuanyuan Liang, Qingzheng |
author_facet | Zhang, Weidong Chen, Jingfang Wu, Xiaoming Chen, Luyu Wei, Jinxing Xue, Mingqiang Liu, Yuanyuan Liang, Qingzheng |
author_sort | Zhang, Weidong |
collection | PubMed |
description | OBJECTIVE: To investigate the safety and efficacy of preoperative ultra-short-course chemotherapy, combined with surgical treatment for chest wall tuberculosis and summarize our experience in this regard, to provide a reference for national and international clinicians. METHODS: A retrospective analysis was conducted of the clinical data, preoperative anti-tuberculosis duration, and postoperative recurrence rate in 263 patients with chest wall tuberculosis spanning 5 years. RESULTS: Overall, 263 patients were treated with anti-tuberculosis drugs for about [Image: see text] ± 12.49 days during the preoperative period. Simple chest wall tuberculosis was treated for [Image: see text] ± 5.87 days and composite chest wall tuberculosis for [Image: see text] ± 5.11 days. The postoperative recurrence rate of chest wall tuberculosis was 3.80%, which was close to or lower than the recurrence rate of routine preoperative anti-tuberculous therapy in patients subjected to ultra-short-range anti-tuberculosis treatment before surgery. CONCLUSION: Preoperative ultra-short-course chemotherapy combined with surgical treatment of chest wall tuberculosis did not increase the recurrence rate of chest wall tuberculosis; moreover, it could effectively shorten hospitalization time and improve patient compliance. Full-line anti-tuberculosis treatment and complete resolution of tuberculosis infections are crucial to curing chest wall tuberculosis. |
format | Online Article Text |
id | pubmed-7381815 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-73818152020-08-05 Preoperative Ultra-Short-Course Chemotherapy Combined with Surgery for the Treatment of Chest Wall Tuberculosis Zhang, Weidong Chen, Jingfang Wu, Xiaoming Chen, Luyu Wei, Jinxing Xue, Mingqiang Liu, Yuanyuan Liang, Qingzheng Infect Drug Resist Original Research OBJECTIVE: To investigate the safety and efficacy of preoperative ultra-short-course chemotherapy, combined with surgical treatment for chest wall tuberculosis and summarize our experience in this regard, to provide a reference for national and international clinicians. METHODS: A retrospective analysis was conducted of the clinical data, preoperative anti-tuberculosis duration, and postoperative recurrence rate in 263 patients with chest wall tuberculosis spanning 5 years. RESULTS: Overall, 263 patients were treated with anti-tuberculosis drugs for about [Image: see text] ± 12.49 days during the preoperative period. Simple chest wall tuberculosis was treated for [Image: see text] ± 5.87 days and composite chest wall tuberculosis for [Image: see text] ± 5.11 days. The postoperative recurrence rate of chest wall tuberculosis was 3.80%, which was close to or lower than the recurrence rate of routine preoperative anti-tuberculous therapy in patients subjected to ultra-short-range anti-tuberculosis treatment before surgery. CONCLUSION: Preoperative ultra-short-course chemotherapy combined with surgical treatment of chest wall tuberculosis did not increase the recurrence rate of chest wall tuberculosis; moreover, it could effectively shorten hospitalization time and improve patient compliance. Full-line anti-tuberculosis treatment and complete resolution of tuberculosis infections are crucial to curing chest wall tuberculosis. Dove 2020-07-17 /pmc/articles/PMC7381815/ /pubmed/32765003 http://dx.doi.org/10.2147/IDR.S255740 Text en © 2020 Zhang et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Zhang, Weidong Chen, Jingfang Wu, Xiaoming Chen, Luyu Wei, Jinxing Xue, Mingqiang Liu, Yuanyuan Liang, Qingzheng Preoperative Ultra-Short-Course Chemotherapy Combined with Surgery for the Treatment of Chest Wall Tuberculosis |
title | Preoperative Ultra-Short-Course Chemotherapy Combined with Surgery for the Treatment of Chest Wall Tuberculosis |
title_full | Preoperative Ultra-Short-Course Chemotherapy Combined with Surgery for the Treatment of Chest Wall Tuberculosis |
title_fullStr | Preoperative Ultra-Short-Course Chemotherapy Combined with Surgery for the Treatment of Chest Wall Tuberculosis |
title_full_unstemmed | Preoperative Ultra-Short-Course Chemotherapy Combined with Surgery for the Treatment of Chest Wall Tuberculosis |
title_short | Preoperative Ultra-Short-Course Chemotherapy Combined with Surgery for the Treatment of Chest Wall Tuberculosis |
title_sort | preoperative ultra-short-course chemotherapy combined with surgery for the treatment of chest wall tuberculosis |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381815/ https://www.ncbi.nlm.nih.gov/pubmed/32765003 http://dx.doi.org/10.2147/IDR.S255740 |
work_keys_str_mv | AT zhangweidong preoperativeultrashortcoursechemotherapycombinedwithsurgeryforthetreatmentofchestwalltuberculosis AT chenjingfang preoperativeultrashortcoursechemotherapycombinedwithsurgeryforthetreatmentofchestwalltuberculosis AT wuxiaoming preoperativeultrashortcoursechemotherapycombinedwithsurgeryforthetreatmentofchestwalltuberculosis AT chenluyu preoperativeultrashortcoursechemotherapycombinedwithsurgeryforthetreatmentofchestwalltuberculosis AT weijinxing preoperativeultrashortcoursechemotherapycombinedwithsurgeryforthetreatmentofchestwalltuberculosis AT xuemingqiang preoperativeultrashortcoursechemotherapycombinedwithsurgeryforthetreatmentofchestwalltuberculosis AT liuyuanyuan preoperativeultrashortcoursechemotherapycombinedwithsurgeryforthetreatmentofchestwalltuberculosis AT liangqingzheng preoperativeultrashortcoursechemotherapycombinedwithsurgeryforthetreatmentofchestwalltuberculosis |