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The Interaction Between Spinal PDGFRβ and μ Opioid Receptor in the Activation of Microglia in Morphine-Tolerant Rats

PURPOSE: Opioid tolerance remains a challenging problem, which limits prolonged drug usage in clinics. Previous studies have shown a fundamental role of platelet-derived growth factor receptor β submit (PDGFRβ) in morphine tolerance. The aim of this study was to investigate the mechanisms of spinal...

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Detalles Bibliográficos
Autores principales: Li, Zheng, Jia, Xiaoqian, Peng, Xiaoling, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381827/
https://www.ncbi.nlm.nih.gov/pubmed/32765055
http://dx.doi.org/10.2147/JPR.S255221