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COVID-19 y tabaquismo: revisión sistemática y metaanálisis de la evidencia
OBJECTIVE: The aim of this study was to determine if tobacco use in patients with Covid-19 is associated with a negative disease course and adverse outcome, and if smoking, current and past, is associated with a greater possibility of developing COVID-19. MATERIAL AND METHODS: A systematic review (S...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SEPAR. Published by Elsevier España, S.L.U.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381922/ https://www.ncbi.nlm.nih.gov/pubmed/34629638 http://dx.doi.org/10.1016/j.arbres.2020.06.024 |
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author | Jiménez-Ruiz, Carlos A. López-Padilla, Daniel Alonso-Arroyo, Adolfo Aleixandre-Benavent, Rafael Solano-Reina, Segismundo de Granda-Orive, José Ignacio |
author_facet | Jiménez-Ruiz, Carlos A. López-Padilla, Daniel Alonso-Arroyo, Adolfo Aleixandre-Benavent, Rafael Solano-Reina, Segismundo de Granda-Orive, José Ignacio |
author_sort | Jiménez-Ruiz, Carlos A. |
collection | PubMed |
description | OBJECTIVE: The aim of this study was to determine if tobacco use in patients with Covid-19 is associated with a negative disease course and adverse outcome, and if smoking, current and past, is associated with a greater possibility of developing COVID-19. MATERIAL AND METHODS: A systematic review (SR) and meta-analysis (MA) of previously published works were performed. The search strategy included all known descriptors for Covid-19 and tobacco and was conducted in different databases. Appropriate statistical models were used to address the effect size in meta-analysis, namely random effects and fixed effects model. RESULTS: Thirty-four articles were identified in the SR of which 19 were included in the MA. Being a smoker or former smoker was shown to be a risk factor for worse progression of Covid-19 infection (OR 1.96, 95% CI, 1.36 - 2.83) and a greater probability of presenting a more critical condition (OR 1.79 95% CI, 1.19 - 2.70). As limitations of the MA, we found that most of the studies analyzed were observational with limited publication bias. Two studies that disagreed with the rest were included, although after withdrawing them from the MA, smoking was maintained as a risk factor for worse progress. CONCLUSION: Current and past smoking produces a more serious clinical form of Covid-19 and more frequently leads to intensive care admission, intubation, and death. |
format | Online Article Text |
id | pubmed-7381922 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SEPAR. Published by Elsevier España, S.L.U. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73819222020-07-28 COVID-19 y tabaquismo: revisión sistemática y metaanálisis de la evidencia Jiménez-Ruiz, Carlos A. López-Padilla, Daniel Alonso-Arroyo, Adolfo Aleixandre-Benavent, Rafael Solano-Reina, Segismundo de Granda-Orive, José Ignacio Arch Bronconeumol Original OBJECTIVE: The aim of this study was to determine if tobacco use in patients with Covid-19 is associated with a negative disease course and adverse outcome, and if smoking, current and past, is associated with a greater possibility of developing COVID-19. MATERIAL AND METHODS: A systematic review (SR) and meta-analysis (MA) of previously published works were performed. The search strategy included all known descriptors for Covid-19 and tobacco and was conducted in different databases. Appropriate statistical models were used to address the effect size in meta-analysis, namely random effects and fixed effects model. RESULTS: Thirty-four articles were identified in the SR of which 19 were included in the MA. Being a smoker or former smoker was shown to be a risk factor for worse progression of Covid-19 infection (OR 1.96, 95% CI, 1.36 - 2.83) and a greater probability of presenting a more critical condition (OR 1.79 95% CI, 1.19 - 2.70). As limitations of the MA, we found that most of the studies analyzed were observational with limited publication bias. Two studies that disagreed with the rest were included, although after withdrawing them from the MA, smoking was maintained as a risk factor for worse progress. CONCLUSION: Current and past smoking produces a more serious clinical form of Covid-19 and more frequently leads to intensive care admission, intubation, and death. SEPAR. Published by Elsevier España, S.L.U. 2021-01 2020-07-25 /pmc/articles/PMC7381922/ /pubmed/34629638 http://dx.doi.org/10.1016/j.arbres.2020.06.024 Text en © 2020 SEPAR. Published by Elsevier España, S.L.U. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Original Jiménez-Ruiz, Carlos A. López-Padilla, Daniel Alonso-Arroyo, Adolfo Aleixandre-Benavent, Rafael Solano-Reina, Segismundo de Granda-Orive, José Ignacio COVID-19 y tabaquismo: revisión sistemática y metaanálisis de la evidencia |
title | COVID-19 y tabaquismo: revisión sistemática y metaanálisis de la evidencia |
title_full | COVID-19 y tabaquismo: revisión sistemática y metaanálisis de la evidencia |
title_fullStr | COVID-19 y tabaquismo: revisión sistemática y metaanálisis de la evidencia |
title_full_unstemmed | COVID-19 y tabaquismo: revisión sistemática y metaanálisis de la evidencia |
title_short | COVID-19 y tabaquismo: revisión sistemática y metaanálisis de la evidencia |
title_sort | covid-19 y tabaquismo: revisión sistemática y metaanálisis de la evidencia |
topic | Original |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381922/ https://www.ncbi.nlm.nih.gov/pubmed/34629638 http://dx.doi.org/10.1016/j.arbres.2020.06.024 |
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