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Human Cardiac Fibroblast Number and Activation State Modulate Electromechanical Function of hiPSC-Cardiomyocytes in Engineered Myocardium

Cardiac tissue engineering using hiPSC-derived cardiomyocytes is a promising avenue for cardiovascular regeneration, pharmaceutical drug development, cardiotoxicity evaluation, and disease modeling. Limitations to these applications still exist due in part to the need for more robust structural supp...

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Detalles Bibliográficos
Autores principales: Rupert, Cassady E., Kim, Tae Yun, Choi, Bum-Rak, Coulombe, Kareen L. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381987/
https://www.ncbi.nlm.nih.gov/pubmed/32724316
http://dx.doi.org/10.1155/2020/9363809