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Sirt6 promotes tumorigenesis and drug resistance of diffuse large B-cell lymphoma by mediating PI3K/Akt signaling

BACKGROUND: Sirtuin 6 (Sirt6) is a highly conserved ADP-ribosylase and NAD+ dependent deacylase, involved in broad cellular processes. This molecule possesses contradictory roles in carcinogenesis, as it has been documented to both suppressing and augmenting tumor growth. This project aimed to explo...

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Detalles Bibliográficos
Autores principales:	Yang, Juan, Li, Ying, Zhang, Ya, Fang, Xiaosheng, Chen, Na, Zhou, Xiangxiang, Wang, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382040/ https://www.ncbi.nlm.nih.gov/pubmed/32711549 http://dx.doi.org/10.1186/s13046-020-01623-w

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