BRCAness digitalMLPA profiling predicts benefit of intensified platinum-based chemotherapy in triple-negative and luminal-type breast cancer

BACKGROUND: We previously showed that BRCA-like profiles can be used to preselect individuals with the highest risk of carrying BRCA mutations but could also indicate which patients would benefit from double-strand break inducing chemotherapy. A simple, robust, and reliable assay for clinical use th...

Descripción completa

Detalles Bibliográficos
Autores principales: Lips, Esther H., Benard-Slagter, Anne, Opdam, Mark, Scheerman, Caroline E., Wesseling, Jelle, Hogervorst, Frans B. L., Linn, Sabine C., Savola, Suvi, Nederlof, Petra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382055/
https://www.ncbi.nlm.nih.gov/pubmed/32711554
http://dx.doi.org/10.1186/s13058-020-01313-7

Ejemplares similares

Ejemplares similares