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Therapeutic potential of CKD-506, a novel selective histone deacetylase 6 inhibitor, in a murine model of rheumatoid arthritis

OBJECTIVES: Histone deacetylase (HDAC) 6 promotes inflammation. We investigated the anti-arthritic effects of CKD-506, a novel HDAC6 inhibitor, in vitro and in a murine model of arthritis as a novel treatment option for rheumatoid arthritis (RA). METHODS: HDAC6 was overexpressed in mouse peritoneal...

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Detalles Bibliográficos
Autores principales:	Park, Jin Kyun, Jang, Yu Jin, Oh, Bo Ram, Shin, Jieun, Bae, Daekwon, Ha, Nina, Choi, Young il, Youn, Gi Soo, Park, Jinseu, Lee, Eun Young, Lee, Eun Bong, Song, Yeong Wook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382061/ https://www.ncbi.nlm.nih.gov/pubmed/32711562 http://dx.doi.org/10.1186/s13075-020-02258-0

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