Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer’s disease

BACKGROUND: Based on amyloid cascade and tau hypotheses, protein biomarkers of different Aβ and tau species in cerebrospinal fluid (CSF) and blood/plasma/serum have been examined to correlate with brain pathology. Recently, unbiased proteomic profiling of these human samples has been initiated to id...

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Detalles Bibliográficos
Autores principales: Wang, Hong, Dey, Kaushik Kumar, Chen, Ping-Chung, Li, Yuxin, Niu, Mingming, Cho, Ji-Hoon, Wang, Xusheng, Bai, Bing, Jiao, Yun, Chepyala, Surendhar Reddy, Haroutunian, Vahram, Zhang, Bin, Beach, Thomas G., Peng, Junmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382148/
https://www.ncbi.nlm.nih.gov/pubmed/32711556
http://dx.doi.org/10.1186/s13024-020-00384-6

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