Cargando…

Increased mitochondrial respiration of adipocytes from metabolically unhealthy obese compared to healthy obese individuals

Among obese subjects, metabolically healthy (MHO) and unhealthy obese (MUHO) subjects exist, the latter being characterized by whole-body insulin resistance, hepatic steatosis, and subclinical inflammation. Insulin resistance and obesity are known to associate with alterations in mitochondrial densi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Böhm, Anja, Keuper, Michaela, Meile, Tobias, Zdichavsky, Marty, Fritsche, Andreas, Häring, Hans-Ulrich, de Angelis, Martin Hrabě, Staiger, Harald, Franko, Andras
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382448/ https://www.ncbi.nlm.nih.gov/pubmed/32709986 http://dx.doi.org/10.1038/s41598-020-69016-9

Ejemplares similares

Metabolic Signatures of Cultured Human Adipocytes from Metabolically Healthy versus Unhealthy Obese Individuals
por: Böhm, Anja, et al.
Publicado: (2014)

Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipocytes
por: Berti, Lucia, et al.
Publicado: (2015)

Preadipocytes of obese humans display gender-specific bioenergetic responses to glucose and insulin
por: Keuper, Michaela, et al.
Publicado: (2018)

Glucose tolerance and insulin sensitivity define adipocyte transcriptional programs in human obesity
por: Gerlini, R., et al.
Publicado: (2018)

Ectopic fat accumulation in human astrocytes impairs insulin action
por: Heni, Martin, et al.
Publicado: (2020)

Common Genetic Variation in the SERPINF1 Locus Determines Overall Adiposity, Obesity-Related Insulin Resistance, and Circulating Leptin Levels
por: Böhm, Anja, et al.
Publicado: (2012)

Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors
por: Keuper, Michaela, et al.
Publicado: (2017)

Common Genetic Variation in the Human FNDC5 Locus, Encoding the Novel Muscle-Derived ‘Browning’ Factor Irisin, Determines Insulin Sensitivity
por: Staiger, Harald, et al.
Publicado: (2013)

On the role of macrophages in the control of adipocyte energy metabolism
por: Keuper, Michaela
Publicado: (2019)

Association of obesity risk SNPs in PCSK1 with insulin sensitivity and proinsulin conversion
por: Heni, Martin, et al.
Publicado: (2010)

Allele Summation of Diabetes Risk Genes Predicts Impaired Glucose Tolerance in Female and Obese Individuals
por: Linder, Katarzyna, et al.
Publicado: (2012)

Exercise and diabetes: relevance and causes for response variability
por: Böhm, Anja, et al.
Publicado: (2015)

IRX5 regulates adipocyte amyloid precursor protein and mitochondrial respiration in obesity
por: Bjune, Jan-Inge, et al.
Publicado: (2018)

Maternal whole blood cell miRNA-340 is elevated in gestational diabetes and inversely regulated by glucose and insulin
por: Stirm, Laura, et al.
Publicado: (2018)

Author Correction: Maternal whole blood cell miRNA-340 is elevated in gestational diabetes and inversely regulated by glucose and insulin
por: Stirm, Laura, et al.
Publicado: (2022)

Common Genetic Variation in the Human CTF1 Locus, Encoding Cardiotrophin-1, Determines Insulin Sensitivity
por: Lutz, Stefan Z., et al.
Publicado: (2014)

DPP4 gene variation affects GLP-1 secretion, insulin secretion, and glucose tolerance in humans with high body adiposity
por: Böhm, Anja, et al.
Publicado: (2017)

The effect of differentiation and TGFβ on mitochondrial respiration and mitochondrial enzyme abundance in cultured primary human skeletal muscle cells
por: Hoffmann, Christoph, et al.
Publicado: (2018)

Excessive fuel availability amplifies the FTO-mediated obesity risk: results from the TUEF and Whitehall II studies
por: Wagner, Róbert, et al.
Publicado: (2017)

Granulocyte colony-stimulating factor (G-CSF): A saturated fatty acid-induced myokine with insulin-desensitizing properties in humans
por: Ordelheide, Anna-Maria, et al.
Publicado: (2016)

Common variation in the sodium/glucose cotransporter 2 gene SLC5A2 does neither affect fasting nor glucose-suppressed plasma glucagon concentrations
por: Ordelheide, Anna-Maria, et al.
Publicado: (2017)

Effects of Genetic Loci Associated with Central Obesity on Adipocyte Lipolysis
por: Strawbridge, Rona J., et al.
Publicado: (2016)

The metabolome profiling of obese and non-obese individuals: Metabolically healthy obese and unhealthy non-obese paradox
por: Chashmniam, Saeed, et al.
Publicado: (2020)

Metabolically Healthy and Unhealthy Normal Weight and Obesity
por: Stefan, Norbert
Publicado: (2020)

Untangling the interplay of genetic and metabolic influences on beta-cell function: Examples of potential therapeutic implications involving TCF7L2 and FFAR1()
por: Wagner, Robert, et al.
Publicado: (2014)

Interleukin-1β Downregulates RBP4 Secretion in Human Adipocytes
por: Kotnik, Primoz, et al.
Publicado: (2013)

Adolescents' Perception of Causes of Obesity: Unhealthy Lifestyles or Heritage?
por: Gonçalves, Helen, et al.
Publicado: (2012)

Editorial: Metabolically Healthy and Unhealthy Obese Children and Adolescents
por: Chiesa, Claudio, et al.
Publicado: (2020)

Adipose Tissue Macrophage Polarization in Healthy and Unhealthy Obesity
por: Ruggiero, Alistaire D., et al.
Publicado: (2021)

Metabolically healthy and unhealthy obesity and the development of lung dysfunction
por: Song, Jae-Uk, et al.
Publicado: (2023)

Lack of Gα(i2) proteins in adipocytes attenuates diet-induced obesity
por: Leiss, Veronika, et al.
Publicado: (2020)

Identification of MicroRNAs Associated with Prediabetic Status in Obese Women
por: Kovac, Leona, et al.
Publicado: (2023)

Differential progression of unhealthy diet-induced hepatocellular carcinoma in obese and non-obese mice
por: Hymel, Emma, et al.
Publicado: (2022)

A computational biology approach of a genome-wide screen connected miRNAs to obesity and type 2 diabetes
por: Gottmann, Pascal, et al.
Publicado: (2018)

Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice
por: Franko, Andras, et al.
Publicado: (2017)

Obesity, Metabolic Syndrome, and Adipocytes
por: Dodson, M. V., et al.
Publicado: (2011)

Adipocyte-Endothelium Crosstalk in Obesity
por: Sabaratnam, Rugivan, et al.
Publicado: (2021)

Unbiased analysis of obesity related, fat depot specific changes of adipocyte volumes and numbers using light sheet fluorescence microscopy
por: Theobalt, Natalie, et al.
Publicado: (2021)

Fetuin-A Induces Cytokine Expression and Suppresses Adiponectin Production
por: Hennige, Anita M., et al.
Publicado: (2008)

Peroxisome proliferator-activated receptor gamma (PPARG) modulates free fatty acid receptor 1 (FFAR1) dependent insulin secretion in humans
por: Wagner, Robert, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ehkdk5djc0i3g199vmckp21bt8