Sequential immunization induces strong and broad immunity against all four dengue virus serotypes

A major challenge in dengue vaccine development is the need to induce immunity against four dengue (DENV) serotypes. Dengvaxia®, the only licensed dengue vaccine, consists of four variant dengue antigens, one for each serotype. Three doses of immunization with the tetravalent vaccine induced only su...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Jue, Shrivastava, Shubham, Loo, Hooi Linn, Wong, Lan Hiong, Ooi, Eng Eong, Chen, Jianzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382454/
https://www.ncbi.nlm.nih.gov/pubmed/32728482
http://dx.doi.org/10.1038/s41541-020-00216-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382454/
https://www.ncbi.nlm.nih.gov/pubmed/32728482
http://dx.doi.org/10.1038/s41541-020-00216-0

Ejemplares similares