Cargando…
Low expression of ANT1 confers oncogenic properties to rhabdomyosarcoma tumor cells by modulating metabolism and death pathways
Rhabdomyosarcoma (RMS) is the most frequent form of pediatric soft-tissue sarcoma. It is divided into two main subtypes: ERMS (embryonal) and ARMS (alveolar). Current treatments are based on chemotherapy, surgery, and radiotherapy. The 5-year survival rate has plateaued at 70% since 2000, despite se...
Autores principales: | Vial, J., Huchedé, P., Fagault, S., Basset, F., Rossi, M., Geoffray, J., Soldati, H., Bisaccia, J., Elsensohn, M. H., Creveaux, M., Neves, D., Blay, J. Y., Fauvelle, F., Bouquet, F., Streichenberger, N., Corradini, N., Bergeron, C., Maucort-Boulch, D., Castets, P., Carré, M., Weber, K., Castets, M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382490/ https://www.ncbi.nlm.nih.gov/pubmed/32728477 http://dx.doi.org/10.1038/s41420-020-00302-1 |
Ejemplares similares
-
The Intricate Epigenetic and Transcriptional Alterations in Pediatric High-Grade Gliomas: Targeting the Crosstalk as the Oncogenic Achilles’ Heel
por: Huchedé, Paul, et al.
Publicado: (2022) -
Complex Elucidation of Cells-of-Origin in Pediatric Soft Tissue Sarcoma: From Concepts to Real Life, Hide-and-Seek through Epigenetic and Transcriptional Reprogramming
por: Savary, Clara, et al.
Publicado: (2022) -
Caspase-8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma
por: Locquet, Marie-Anaïs, et al.
Publicado: (2021) -
Conditional generation of free radicals by selective activation of alkoxyamines: towards more effective and less toxic targeting of brain tumors
por: Piris, Patricia, et al.
Publicado: (2023) -
The TOR Pathway at the Neuromuscular Junction: More Than a Metabolic Player?
por: Castets, Perrine, et al.
Publicado: (2020)