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Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine
Mycobacterium tuberculosis is a pathogen with a unique cell envelope including very long fatty acids, implicated in bacterial resistance and host immune modulation. FasR is a TetR-like transcriptional activator that plays a central role in sensing mycobacterial long-chain fatty acids and regulating...
Autores principales: | Lara, Julia, Diacovich, Lautaro, Trajtenberg, Felipe, Larrieux, Nicole, Malchiodi, Emilio L., Fernández, Marisa M., Gago, Gabriela, Gramajo, Hugo, Buschiazzo, Alejandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382501/ https://www.ncbi.nlm.nih.gov/pubmed/32710080 http://dx.doi.org/10.1038/s41467-020-17504-x |
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