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Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine

Mycobacterium tuberculosis is a pathogen with a unique cell envelope including very long fatty acids, implicated in bacterial resistance and host immune modulation. FasR is a TetR-like transcriptional activator that plays a central role in sensing mycobacterial long-chain fatty acids and regulating...

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Detalles Bibliográficos
Autores principales:	Lara, Julia, Diacovich, Lautaro, Trajtenberg, Felipe, Larrieux, Nicole, Malchiodi, Emilio L., Fernández, Marisa M., Gago, Gabriela, Gramajo, Hugo, Buschiazzo, Alejandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382501/ https://www.ncbi.nlm.nih.gov/pubmed/32710080 http://dx.doi.org/10.1038/s41467-020-17504-x

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