Cargando…

Cilostazol for Secondary Prevention of Stroke and Cognitive Decline: Systematic Review and Meta-Analysis

BACKGROUND AND PURPOSE: Cilostazol, a phosphodiesterase 3’ inhibitor, is used in Asia-Pacific countries for stroke prevention, but rarely used elsewhere. In addition to weak antiplatelet effects, it stabilizes endothelium, aids myelin repair and astrocyte-neuron energy transfer in laboratory models,...

Descripción completa

Detalles Bibliográficos
Autores principales:	McHutchison, Caroline, Blair, Gordon W., Appleton, Jason P., Chappell, Francesca M., Doubal, Fergus, Bath, Philip M., Wardlaw, Joanna M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Original Contributions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382534/ https://www.ncbi.nlm.nih.gov/pubmed/32646330 http://dx.doi.org/10.1161/STROKEAHA.120.029454

Ejemplares similares

Effects of Cilostazol and Isosorbide Mononitrate on Cerebral Hemodynamics in the LACI-1 Randomized Controlled Trial
por: Blair, Gordon W., et al.
Publicado: (2021)

Effects of Isosorbide Mononitrate and/or Cilostazol on Hematological Markers, Platelet Function, and Hemodynamics in Patients With Lacunar Ischaemic Stroke: Safety Data From the Lacunar Intervention-1 (LACI-1) Trial
por: Appleton, Jason P., et al.
Publicado: (2019)

Tolerability, safety and intermediary pharmacological effects of cilostazol and isosorbide mononitrate, alone and combined, in patients with lacunar ischaemic stroke: The LACunar Intervention-1 (LACI-1) trial, a randomised clinical trial
por: Blair, Gordon W., et al.
Publicado: (2019)

Clinically Confirmed Stroke With Negative Diffusion-Weighted Imaging Magnetic Resonance Imaging: Longitudinal Study of Clinical Outcomes, Stroke Recurrence, and Systematic Review
por: Makin, Stephen D.J., et al.
Publicado: (2015)

Impact of Small Vessel Disease Progression on Long-term Cognitive and Functional Changes After Stroke
por: Clancy, Una, et al.
Publicado: (2022)

Cilostazol and isosorbide mononitrate for the prevention of progression of cerebral small vessel disease: baseline data and statistical analysis plan for the Lacunar Intervention Trial-2 (LACI-2) (ISRCTN14911850)
por: Bath, Philip M, et al.
Publicado: (2022)

Stability of Estimated Premorbid Cognitive Ability over Time after Minor Stroke and Its Relationship with Post-Stroke Cognitive Ability
por: McHutchison, Caroline A., et al.
Publicado: (2019)

Functional, cognitive and physical outcomes 3 years after minor lacunar or cortical ischaemic stroke
por: McHutchison, Caroline A, et al.
Publicado: (2019)

Clinical management of cerebral small vessel disease: a call for a holistic approach
por: Clancy, Una, et al.
Publicado: (2021)

Little Association between Intracranial Arterial Stenosis and Lacunar Stroke
por: Wardlaw, Joanna M., et al.
Publicado: (2010)

Effect of Glyceryl Trinitrate on Hemodynamics in Acute Stroke: Data From the ENOS Trial
por: Appleton, Jason P., et al.
Publicado: (2019)

Use of dynamic contrast-enhanced MRI to measure subtle blood–brain barrier abnormalities()
por: Armitage, Paul A., et al.
Publicado: (2011)

Endothelial Function, Inflammation, Thrombosis, and Basal Ganglia Perivascular Spaces in Patients with Stroke
por: Wang, Xin, et al.
Publicado: (2016)

Protocol: The Lacunar Intervention Trial 2 (LACI-2). A trial of two repurposed licenced drugs to prevent progression of cerebral small vessel disease
por: Wardlaw, Joanna, et al.
Publicado: (2020)

The effect of different combinations of vascular, dependency and cognitive endpoints on the sample size required to detect a treatment effect in trials of treatments to improve outcome after lacunar and non-lacunar ischaemic stroke
por: Makin, Stephen DJ, et al.
Publicado: (2017)

Relationship Between Venules and Perivascular Spaces in Sporadic Small Vessel Diseases
por: Jochems, Angela C.C., et al.
Publicado: (2020)

Associations of Clinical Stroke Misclassification (‘Clinical-Imaging Dissociation’) in Acute Ischemic Stroke
por: Potter, Gillian, et al.
Publicado: (2010)

Association between Striatal Brain Iron Deposition, Microbleeds and Cognition 1 Year After a Minor Ischaemic Stroke
por: Valdés Hernández, Maria del C., et al.
Publicado: (2019)

Isosorbide Mononitrate and Cilostazol Treatment in Patients With Symptomatic Cerebral Small Vessel Disease: The Lacunar Intervention Trial-2 (LACI-2) Randomized Clinical Trial
por: Wardlaw, Joanna M., et al.
Publicado: (2023)

Intracranial Carotid Calcification on Cranial Computed Tomography: Visual Scoring Methods, Semiautomated Scores, and Volume Measurements in Patients With Stroke
por: Subedi, Deepak, et al.
Publicado: (2015)

How Much Do Focal Infarcts Distort White Matter Lesions and Global Cerebral Atrophy Measures?
por: Wang, Xin, et al.
Publicado: (2012)

Cognitive ability, education and socioeconomic status in childhood and risk of post-stroke depression in later life: A systematic review and meta-analysis
por: Backhouse, Ellen V., et al.
Publicado: (2018)

Intracranial Bleeding After Reperfusion Therapy in Acute Ischaemic Stroke Patients Randomized to Glyceryl Trinitrate vs. Control: An Individual Patient Data Meta-Analysis
por: Appleton, Jason P., et al.
Publicado: (2020)

Corrigendum: Intracranial Bleeding After Reperfusion Therapy in Acute Ischaemic Stroke Patients Randomized to Glyceryl Trinitrate vs. Control: An Individual Patient Data Meta-Analysis
por: Appleton, Jason P., et al.
Publicado: (2020)

Neuropsychiatric symptoms as a sign of small vessel disease progression in cognitive impairment
por: Clancy, Una, et al.
Publicado: (2022)

Predictors of Lesion Cavitation After Recent Small Subcortical Stroke
por: Gattringer, Thomas, et al.
Publicado: (2019)

Enlarged perivascular spaces and cerebral small vessel disease
por: Potter, Gillian M, et al.
Publicado: (2015)

Advanced Neuroimaging of Cerebral Small Vessel Disease
por: Blair, Gordon W., et al.
Publicado: (2017)

Cilostazol for Secondary Prevention of Stroke: Should the Guidelines Perhaps Be Extended?
por: Galyfos, George, et al.
Publicado: (2017)

Cilostazol for secondary stroke prevention: systematic review and meta-analysis
por: Tan, Choon Han, et al.
Publicado: (2021)

Stroke subtype, vascular risk factors, and total MRI brain small-vessel disease burden
por: Staals, Julie, et al.
Publicado: (2014)

Intracranial hemodynamic relationships in patients with cerebral small vessel disease
por: Blair, Gordon W., et al.
Publicado: (2020)

Improving Clinical Detection of Acute Lacunar Stroke: Analysis From the IST-3
por: Arba, Francesco, et al.
Publicado: (2020)

Assessing Brain Tissue Viability on Nonenhanced Computed Tomography After Ischemic Stroke
por: Alzahrani, Awad, et al.
Publicado: (2023)

Systematic study of cilostazol on secondary stroke prevention: a meta-analysis
por: Qian, Yining, et al.
Publicado: (2013)

Clinical diagnosis of TIA or minor stroke and prognosis in patients with neurological symptoms: A rapid access clinic cohort
por: Graham, Catriona, et al.
Publicado: (2019)

Core Outcome Measures for Palliative and End-of-Life Research After Severe Stroke: Mixed-Method Delphi Study
por: Mason, Bruce, et al.
Publicado: (2021)

Blood pressure management in acute stroke
por: Appleton, Jason P, et al.
Publicado: (2016)

Longitudinal Changes of White Matter Hyperintensities in Sporadic Small Vessel Disease: A Systematic Review and Meta-analysis
por: Jochems, Angela C.C., et al.
Publicado: (2022)

Accuracy of artificial intelligence software for CT angiography in stroke
por: Mair, Grant, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_dsi7laud8r14m6ns4og1vquqkd